[Acute leukemia associated with Down syndrome: clinical analysis of 21 cases].

Objective: To summarize the clinical characteristics, laboratory findings and prognosis of patients with Down syndrome-related acute leukemia (DS-AL).

Methods: The clinical data, laboratory findings, chemotherapy and prognosis of 21 children with DS-AL were analyzed.

Results: Most of the children had disease onset of leukemia at 1 to 5 years of age (85.