Publications by authors named "Yun-Luo Lv"
The aim of the present study was to compare the effects of α-lipoic acid (ALA) on postoperative cognitive dysfunction (POCD) between wild type (WT) and leptin receptor-deficient (db/db) mice and to elucidate the underlying mechanism of treatment with ALA. The present study compared the effects of ALA on spatial learning and memory of WT and db/db mice using a Morris water maze following hepatectomy. The expression levels of proteins, including cyclin-dependent kinase 5 (Cdk5), tau, phosphorylated tau and amyloid β (Aβ) were measured in the hippocampus.
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- The study investigated risk factors for postoperative cognitive dysfunction (POCD) in colorectal surgery patients, emphasizing its links to age, comorbidities, and prolonged ICU stays.
- Nineteen out of eighty patients (24.7%) were diagnosed with POCD, with significant risk factors identified: a history of diabetes, fasting for more than three days post-surgery, and an SIRS score greater than 3 on the second day after surgery.
- The findings highlight the importance of monitoring these factors to potentially reduce the occurrence of early POCD in colorectal cancer patients.