Publications by authors named "Yun-Lan Xie"
Article Synopsis
- ERK1/2 is phosphorylated and activated during environmental stress, like epileptiform discharge, influencing abnormal axon growth and synapse changes in neurons.
- Neurons were tested in a controlled environment without magnesium, and the effects of the ERK1/2 inhibitor U0126 were compared at various time points following discharge.
- The presence of phosphorylated ERK1/2, C-fos, GAP-43, and synaptophysin increased together after discharge, while inhibition of ERK1/2 led to a reduction in these markers, suggesting ERK1/2's role in promoting changes related to epilepsy.
