Publications by authors named "Yun-Ji Jeong"
Article Synopsis
- Triple negative breast cancer (TNBC) is aggressive and lacks specific receptors, making it hard to treat, with paclitaxel being a common anticancer drug used.
- In a study with TNBC cells, a small number of cells survived after treatment with paclitaxel, leading to the emergence of a new highly proliferative and tumorigenic cell line called MDA-MB-231-JYJ.
- These new cells showed resistance to dasatinib, a drug inhibiting certain cancer pathways, suggesting that patients undergoing treatment may develop resistance, highlighting the need for careful clinical trial designs involving these agents.
NgR1 Expressed in P19 Embryonal Carcinoma Cells Differentiated by Retinoic Acid Can Activate STAT3.
Korean J Physiol Pharmacol
March 2015
Article Synopsis
- * Research involved inducing P19 embryonal carcinoma cells to become neuron-like cells, and during this process, they expressed both NgR1 and NMDA receptors, indicating they retained some neural characteristics.
- * The study suggests that these neuronally differentiated P19 cells could be a useful in vitro model for exploring how NgR1 and its associated pathways work, as well as testing potential drugs that could influence NgR1 activity.