Inhibitory kinetics of chlorocinnamic acids on mushroom tyrosinase.

Tyrosinase (EC 1.14.18.

Antityrosinase and antimicrobial activities of furfuryl alcohol, furfural and furoic acid.

The inhibitory kinetics of furfuryl alcohol, furfural and furoic acid on mushroom tyrosinase have been investigated. The results showed that these furan compounds were reversible inhibitors of the enzyme. Furthermore, furfuryl alcohol and furfural were found to be mixed-type inhibitors while furoic acid is uncompetitive inhibitor.

Inhibitory effects of naphthols on the activity of mushroom tyrosinase.

Tyrosinase (EC 1.14.18.

Inhibitory effects of fatty acids on the activity of mushroom tyrosinase.

The effects of fatty acids, octanoic acid, (2E, 4E)-hexa-2,4-dienoic acid, hexanoic acid, (2E)-but-2-enoic acid, and butyric acid on the activities of mushroom tyrosinase have been investigated. The results showed that the fatty acids can potently inhibit both monophenolase activity and diphenolase activity of tyrosinase, and that the unsaturated fatty acids exhibited stronger inhibitory effect against tyrosinase than the corresponding saturated fatty acids, and the inhibitory effects were enhanced with the extendability of the fatty acid chain. For the monophenolase activity, the fatty acids could not only lengthen the lag period, but also decrease the steady-state activities.

Antityrosinase and antimicrobial activities of trans-cinnamaldehyde thiosemicarbazone.

Tyrosinase (EC 1.14.18.