Publications by authors named "Yun-Fei Feng"
Mol Neurobiol
January 2024
Article Synopsis
- Postpartum depression significantly affects both mothers and infants, yet the underlying mechanisms are not fully understood.
- Recent research indicates that extrasynaptic GABA receptors play a crucial role in this condition, impacting neuron function through tonic inhibition.
- Changes in these receptors during pregnancy and childbirth may contribute to postpartum depression, suggesting that targeting them could lead to new treatment options.
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Front Pharmacol
October 2022
Article Synopsis
- - The study investigated the efficacy and safety of a new anesthetic called remimazolam compared to propofol during fiberoptic bronchoscopy, using a randomized clinical trial with 154 subjects.
- - Results showed that both anesthetics were effective, with remimazolam having a similar sedative effect but slightly longer times for loss of consciousness and awakening compared to propofol.
- - Importantly, remimazolam demonstrated lower rates of hypotension and injection pain than propofol, suggesting it may be a safer option for patients undergoing bronchoscopy.
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Article Synopsis
- The research analyzed clinical data from hypertensive patients admitted to the Endocrinology Division to distinguish between essential and secondary hypertension, providing insights for better differential diagnosis.
- A total of 1,001 hospitalized cases were reviewed, finding that 34.6% had essential hypertension while 65.4% had secondary hypertension, with adrenal hypertension being the most common secondary cause.
- Logistic regression showed significant differentiating factors, with family history and BMI being strong predictors for essential hypertension, while adrenal masses and specific aldosterone levels were linked to secondary hypertension.
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J Zhejiang Univ Sci B
November 2010
Article Synopsis
- Fulminant type 1 diabetes is a newly identified subtype characterized by extremely quick destruction of insulin-producing β-cells, leading to rapid hyperglycemia and diabetic ketoacidosis.
- A case study of a 45-year-old Chinese woman who suddenly experienced excessive thirst and urination after flu-like symptoms illustrates this condition, showing a normal HbA1c but high blood glucose and severe insulin deficiency.
- The findings suggest a possible link between HLA-DR7 and the predisposition to fulminant type 1 diabetes, particularly among Chinese individuals.
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Mol Biol Rep
November 2009
Article Synopsis
- The study investigates how puerarin affects the expression of RAGE (receptor for advanced glycation end products) mRNA in the kidneys of diabetic rats induced by streptozotocin (STZ).
- Thirty male Sprague-Dawley rats were divided into three groups: one receiving puerarin, one diabetic control, and a normal control, with various diabetes indicators measured over eight weeks.
- Results indicated that puerarin significantly reduced body weight, blood glucose levels, and RAGE mRNA expression in diabetic rats, suggesting it may help protect renal tissue from damage caused by high blood sugar and AGEs.
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