Effects of Hydroxychloroquine on Proteinuria in IgA Nephropathy: A Randomized Controlled Trial.

Rationale & Objective: Despite optimization of renin-angiotensin-aldosterone system (RAAS) inhibition, patients with immunoglobulin A nephropathy (IgAN) and persistent proteinuria remain at risk for kidney failure. We evaluated the efficacy and safety of hydroxychloroquine (HCQ), an immunomodulator, when added to the treatment regimen of patients with IgAN.

Study Design: Double-blind, randomized, placebo-controlled, phase 2 clinical trial.

[Clinical efficacy of acne scar treatment with micro-plasma radio frequency].

Objective: To explore the efficacy of facial acne scars treatment with micro-plasma radio frequency.

Methods: A total of 24 patients with facial acne scars underwent micro-plasma treatment for 3 - 5 times. And their efficacies were evaluated by the patient photographs before and 2 months after treatment.