Publications by authors named "Yun-Chin Huang"
Article Synopsis
- The survival rate for breast cancer is over 90%, but it drops to below 30% once it spreads to other organs, with triple-negative breast cancer (TNBC) comprising 15-20% of cases and having worse outcomes due to fewer treatment options.
- High levels of Carboxyl-terminal modulator protein (CTMP) are linked to worse recurrence and disease-free survival in TNBC patients, as CTMP enhances cell migration and invasion in certain cancer cell lines.
- CTMP influences TNBC metastasis through the Akt pathway, and targeting this pathway could offer new therapeutic strategies, indicating that CTMP might serve as a diagnostic marker for assessing patient prognosis.
Background/purpose: Taiwan is only now beginning to offer palliative care to patients who do not have cancer. This study aimed to document the polysymptomatic presentation of illness in Taiwanese patients with late-stage nonmalignant disease and to evaluate the potential benefits of palliative care for these patients. The results may help to educate healthcare personnel regarding the need for and importance of palliative treatment as comprehensive, appropriate end-of-life care for patients with nonmalignant disease.
View Article and Find Full Text PDFWhen it comes to end-of-life care, chronic obstructive pulmonary disease (COPD) patients are often treated differently from lung cancer patients. However, few reports have compared end-of-life care between these two groups. We investigated the differences between patients with end-stage COPD and end-stage lung cancer based on end-of-life symptoms and clinical practice patterns using a retrospective study of COPD and lung cancer patients who died in an acute care hospital in Taiwan.
View Article and Find Full Text PDFObjectives: To investigate how hyaluronic acid (HA) affects nerve growth factor (NGF) production and bladder overactivity in a cyclophosphamide (CYP)-induced cystitis rat model.
Methods: Female Sprague-Dawley rats received three intermittent intraperitoneal injections of CYP (75 mg/kg) or saline. Before or after CYP injection, HA was given intravesically and urine NGF was checked with creatinine correction.