Publications by authors named "Yun-Chiao Huang"

Flexible pressure sensors that can robustly mimic the function of slow-adapting type I (SA-I) mechanoreceptors are essential for realizing human-like object manipulation in artificial intelligent (AI) robots or amputees. Here, we report a straightforward approach to highly sensitive and robust flexible pressure sensors with fast response time and low operating voltage based on conductive micropyramids made of polydimethylsiloxane/carbon nanotube composites. Both numerical simulations and experimental studies show that the pressure-sensing properties of the devices can be systematically tuned by the spatial arrangement of micropyramids.

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A fundamental understanding of the charge transport mechanism in two-dimensional semiconductors (e.g., MoS) is crucial for fully exploring their potential in electronic and optoelectronic devices.

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Article Synopsis
  • Artificial superlattices created from van der Waals heterostructures of 2D atomic crystals, like graphene and molybdenum disulfide, present new technological possibilities but face challenges in forming stable and reproducible structures.
  • Traditional methods for building these superlattices, such as layer-by-layer techniques or chemical-vapour deposition, are either tedious or ineffective for complex arrangements.
  • A novel approach using electrochemical molecular intercalation leads to stable superlattices by alternating monolayer atomic crystals with molecular layers, resulting in enhanced electrical properties and the potential for diverse applications across various 2D materials.
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The preparation of alkyl chain-grafted poly(l-lysine) (PLL) vesicles with tunable molecular assembly in aqueous solution and the evaluation of their membrane permeability by drug release experiments have been investigated. Upon grafting long alkyl chains, polypeptides confined in the assembled nanostructures adopted ordered conformations such as α-helices or β-sheets/turns, leading to the dense packing of membranes and, consequently, the decreases in vesicular size and membrane permeability. The vesicles can also be cross-linked by genipin to form stable structures with tunable membrane permeability.

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The fibrillation of hen egg-white lysozyme (HEWL) in the absence and presence of simple, unstructured D,L-lysine-co-glycine (D,L-Lys-co-gly) and D,L-lysine-co-L-phenylalanine (D,L-Lys-co-Phe) copolypeptides was studied by using a variety of analytical techniques. The attenuating and decelerating effects on fibrillation are significantly dependent on the polypeptide concentration and the composition ratios in the polypeptide chain. Interestingly, D,L-Lys-co-gly and D,L-Lys-co-Phe copolypeptides with the same composition ratio have comparable attenuating effects on fibrillation.

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