Effect of sequential nursing care combined with communication intervention on visual recovery and pain after cataract ultrasound emulsification.

Background: Cataracts are a common ophthalmic disease and postoperative vision recovery is crucial to patient quality of life. Rational and efficient care models play an important role in promoting vision recovery.

Aim: To evaluate the clinical effectiveness of procedural nursing care combined with communication intervention in vision recovery after cataract ultrasound emulsification.

[The role of adenine nucleotide and its metabolites in regulating the homeostasis of glucose and lipid metabolism].

Glucose and lipid metabolism is the most fundamental metabolic activity of higher organisms. This process is affected by both genetic polymorphisms and environmental factors. Excessive uptake and accumulation of lipids lead to obesity and disorder of glucose metabolic homeostasis characterized by insulin resistance and hyperglycemia, suggesting that the cross-regulation between lipid and glucose metabolism happens precisely at organ, cellular and molecular levels by known mechanisms.

[Clinical application of testicular aspiration biopsy by continuous negative-pressure puncture].

Objective: To investigate the characteristics of testicular aspiration biopsy by continuous negative-pressure puncture (CNPP) and sum up the preliminary experience in employing this strategy.

Methods: Totally, 271 patients underwent testicular aspiration biopsy in our hospital from August 2002 to December 2014, 88 by open testicular extraction (group A), 87 with a biopsy gun needle (group B), and 96 with a CNPP device (group C). We analyzed the clinical data about the patients and compared the operation time, intraoperative blood loss, postoperative complications, and the success rate of sperm retrieval among the three groups.

Effects of photoperiod on growth, lipid metabolism and oxidative stress of juvenile gibel carp (Carassius auratus).

A 58-day cultivation experiment was carried out to investigate the effects of photoperiods on growth, lipid metabolism and oxidative stress of juvenile gibel carp. Juveniles (5.41 ± 0.

Cyclotriphosphazene core-based dendrimers for biomedical applications: an update on recent advances.

This review is focused on the recent use of cyclotriphosphazene-based dendrimers in biomedicine. Since its synthesis for the first time in 1834, cyclotriphosphazene has been an important compound of phosphorus chemistry as a scaffold, and a large number of cyclotriphosphazene derivatives have been synthesized and applied in various fields such as biology, catalysis, fluorescence, nanomaterials, etc. Today, one of the most important uses concerns its biomedical applications.

Enhancing alkaline hydrogen evolution reaction activity through Ni-Mn3O4 nanocomposites.

Developing efficient, stable and cost-effective electrocatalysts towards hydrogen production in alkaline environments is vital to improve energy efficiency for water splitting. In this work, we prepared Ni-Mn3O4 nanocomposites on Ni foam which exhibit an excellent hydrogen evolution reaction catalytic activity with a current density (j) of 10 mA cm(-2) at an overpotential (η) of 91 mV and show good stability in an alkaline medium.

1-(2-Carb-oxy-eth-yl)-3-(carboxyl-atometh-yl)-2-ethyl-benzimidazol-1-ium monohydrate.

In the title compound, C14H16N2O4·H2O, three substituent groups are located on the same side of the benzimidazole ring plane. In the crystal, O-H⋯O hydrogen bonds and π-π stacking between parallel imidazole rings [centroid-centroid distance = 3.858 (4) Å] link the mol-ecules into a three-dimensional supra-molecular structure.

A one-dimensional silver(I) coordination polymer based on the 2-[2-(pyridin-4-yl)-1H-benzimidazol-1-ylmethyl]phenol ligand exhibiting photoluminescence.

A one-dimensional Ag(I) coordination complex, catena-poly[[silver(I)-μ-{2-[2-(pyridin-4-yl)-1H-benzimidazol-1-ylmethyl]phenol-κ(2)N(2):N(3)}] perchlorate monohydrate], {[Ag(C19H15N3O)]ClO4·H2O}n, was synthesized by the reaction of 2-[2-(pyridin-4-yl)-1H-benzimidazol-1-ylmethyl]phenol (L) with silver perchlorate. In the complex, the L ligands are arranged alternately and link Ag(I) cations through one benzimidazole N atom and the N atom of the pyridine ring, leading to an extended zigzag chain structure. In addition, the one-dimensional chains are extended into a three-dimensional supramolecular architecture via O-H···O hydrogen-bond interactions and π-π stacking interactions.

[Function analysis of Sj34.9 gene based on RNAi and microarray].

Objective: To analyze the function of Sj34.9 gene, so as to provide the reference for future studies.

Methods: The Sj34.

2-[2-(3-Methyl-but-oxy)-5-nitro-benz-amido]-acetic acid dimethyl sulfoxide monosolvate.

In the title compound, C(14)H(18)N(2)O(6)·C(2)H(6)OS, the -C(O)NHCH(2)CO(2)H and -O(CH(2))(2)CH(CH(3))(2) substitutents of the aromatic ring are positioned such that the -NH- group is hydrogen-bond donor to the ether O atom of the other substituent. The dimethyl sulfoxide solvent mol-ecule is linked to the carb-oxy-lic acid group by an O-H⋯O hydrogen bond.

Bis(tetra-methyl-ammonium) thio-sulfate tetra-hydrate.

The anion of the title salt, 2C(4)H(12)N(+)·S(2)O(3) (2-)·4H(2)O, possesses approximate C(3v) symmetry. The water mol-ecules themselves engage in hydrogen bonding, forming a ribbon running along the a axis; adjacent chains are linked to the thio-sulfate anions by hydrogen bonds, forming a three-dimensional network. The cavities in the network are occupied by the tetra-methyl-ammonium counter ions.

Inhibition of TNF-α/IFN-γ induced RANTES expression in HaCaT cell by naringin.

Context: Naringin is a bioflavonoid derivative and is predominantly found in Citrus paradisi Macf., Citrus sinensis (Linn.) Osbeck, Citrus unshiu Marc.

In vivo biodistribution, anti-inflammatory, and hepatoprotective effects of liver targeting dexamethasone acetate loaded nanostructured lipid carrier system.

We aimed to evaluate whether the enhancement of the liver accumulation and anti-inflammatory activity of dexamethasone acetate (DXMA) could be achieved by incorporating it into nanostructured lipid carrier (NLCs). DXMA-NLCs were prepared using a film dispersion-ultrasonication method and characterized in terms of particle size, PDI, zeta potential, differential scanning calorimetry, drug loading capacity, encapsulation efficiency, and in vitro release. The biodistribution and pharmacokinetics of DXMA-NLCs in mice were significantly different from those of the DXMA solution (DXMA-sol).

[Study on beta-amyloid peptide 1-42 induced chemokine RANTES in U251 cell].

Objective: To study the molecular mechanisms of beta-amyloid 1-42 (Abeta1.42) induced the inflammatory response in U251 cells.

Methods: U251 cells were treated with different concentration of Abeta1-42 (0.

4-(4-Hydroxybenzoyl)phenol mono-hydrate.

The aromatic rings of the title compound, C(13)H(10)O(3)·H(2)O, are aligned at dihedral angles of 20.6 (1) and 40.8 (1)° with respect to the triangular C(ar-yl)-C(=O)-C(ar-yl) fragment.

[In vitro release study, in vivo evaluation of biodistribution and antitumor activity of HPMA copolymer-5-fluorouracil conjugates].

The in vitro release behavior, in vivo biodistribution and antitumor activity of N-(2-hydroxypropyl) methacrylamide (HPMA) copolymer-5-fluorouracil conjugates (P-FU) were studied. The in vitro release behavior was evaluated by determining the amount of 5-fluorouracil (5-FU) released from P-FU in mice plasma at 37 degrees C. The in vivo biodistribution and therapeutic evaluation were investigated with Kunming mice bearing hepatoma 22 (H22).

Tetra-n-propyl-ammonium chloride monohydrate.

The crystal structure of the title salt hydrate, C(12)H(28)N(+)·Cl(-)·H(2)O, consists of non-inter-acting cations and anions. The water mol-ecule forms hydrogen bonds to two chloride ions, about a center of inversion, generating a planar eight-membered {⋯H-O-H⋯Cl}(2) ring.

Tetra-n-propyl-ammonium acetate-boric acid (1/1).

In the crystal structure of the ammonium carboxyl-ate-boric acid cocrystal, (C(3)H(7))(4)N(+)·CH(3)CO(2) (-)·H(3)BO(3), the boric acid forms two O-H⋯O hydrogen bonds to the acetate anion. The acetate-boric acid species is hydrogen bonded to another acetate-boric acid species through the third OH unit of the boric acid about a twofold rotation axis.

Tris(tetra-ethyl-ammonium) hydrogen bis-[2-(sulfatosulfan-yl)benzoate].

The reaction between tetra-ethyl-ammonium hydroxide and 2,2'-dithio-benzoic acid yields the title compound, 3C(8)H(20)N·H(C(6)H(4)O(5)S(2))(2) (3-), the trianion of which comprises two 2-(sulfato-sulfan-yl)benzoate dianions linked across a center of inversion by an acid H atom. One of the cations is disordered about another center of inversion.

Bis(tetra-methyl-ammonium) oxalate monohydrate.

In the crystal structure of the title hydrated salt, 2C(4)H(12)N(+)·C(2)O(4) (2-)·H(2)O, the two independent cations, the anion and the water mol-ecule all lie on special positions of m site symmetry. In both cations, the mirror plane passes through the nitrogen atom and two methyl groups; in the anion, the mirror plane passes through two carbon and two oxygen atoms. The anions and water mol-ecules inter-act by O-H⋯O hydrogen bonding, forming a chain running along the b axis.

[Antitumor activity of mitoxantrone-nanosphere against murine liver tumor H22].

Objective: [corrected] To make a comparison between mitoxantrone (DHAQ) and liver targeting drug delivery system mitoxantrone-polybutylcyanoacrylate-nanosphere (DHAQ-PBCA-NS) in respect to their antitumor activity against experimental liver tumor H22 in mice.

Methods: Drugs were given intravenously on the 1st, 5th, 9th day after planting tumor respectively. Weight of tumor in mouse was determined and the results were compared with those of mitoxantrone (DHAQ).

PCR-based site-specific mutagenesis of peptide antibiotics FALL-39 and its biologic activities.

Aim: To construct PGEX-1lambdaT-FALL-39 expression vector and its mutant vector, and study the relationship of function and structure.

Methods: A cDNA encoding mature FALL-39 was cloned from SPCA-1 cell mRNA and the prokaryotic expression vector PGEX-1lambdaT-FALL-39 was constructed. Two kinds of polymerase chain reaction (PCR) for the site-direction mutagenesis were used to construct FALL-39 mutant expression vector, FALL-39-Lys-32 and FALL-39-Lys-24.