Mitotane is a drug used to treat adrenal issues, but it has a specific dosage range to avoid complications; exceeding this range can lead to serious side effects.
A 5-year-old girl with signs of early puberty and an adrenal mass was diagnosed with adrenocortical carcinoma and treated with mitotane and radiation, starting with a low dose to monitor levels.
After 6 months on the drug, she developed neurological symptoms and complications from high mitotane levels, leading to further health issues once the medication was stopped, highlighting the need for careful dosage management and monitoring in pediatric patients.