Publications by authors named "Yun Ping Neo"

Article Synopsis
  • Scientists were trying to make more l-isoleucine, which is an important substance, by focusing on a related substance called l-threonine.
  • They created a special mutant strain that blocked certain processes that break down l-threonine, helping it produce 72.3% more l-isoleucine compared to the original strain.
  • They also discovered changes in many genes between the two strains, which helped explain why the mutant was growing better and producing more l-isoleucine.
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Roselle is an annual botanical plant that widely planted in different countries worldwide. Its different parts, including seeds, leaves, and calyces, can offer multi-purpose applications with economic importance. The present review discusses the detailed profile of bioactive compounds present in roselle seeds, leaves, and calyces, as well as their extraction and processing, to explore their potential application in pharmaceutical, cosmetic, nutraceutical, food and other industries.

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Background: Diabetic foot ulcer (DFU) is a major debilitating complication of diabetes. The lack of effective diabetic wound dressings has been a significant problem in DFU management. In this study, we aim to establish a phlorotannin-incorporated nanofibre system and determine its potential in accelerating hyperglycaemic wound healing.

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Over the last decades, three-dimensional (3D) organotypic skin models have received enormous attention as alternative models to animal models and two-dimensional assays. To date, most organotypic skin models have an epidermal layer of keratinocytes and a dermal layer of fibroblasts embedded in an extracellular matrix (ECM)-based biomaterial. The ECM provides mechanical support and biochemical signals to the cells.

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Increasing incidences of chronic wounds urge the development of effective therapeutic wound treatment. As the conventional wound dressings are found not to comply with all the requirements of an ideal wound dressing, the development of alternative and effective dressings is demanded. Over the past few years, electrospun nanofiber has been recognized as a better system for wound dressing and hence has been studied extensively.

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Article Synopsis
  • * Heat curing at 150 °C for 24 hours altered the properties of the fiber mats based on the amount of gallic acid used, including a slower release rate of gallic acid.
  • * This research suggests that heat-cured zein-based fibers may be useful for food packaging applications due to their improved molecular structure and properties after treatment.
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The applicability of gallic acid loaded zein (Ze-GA) electrospun fibre mats towards potential active food packaging material was evaluated. The surface chemistry of the electrospun fibre mats was determined using X-ray photon spectroscopy (XPS). The electrospun fibre mats showed low water activity and whitish colour.

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Gallic acid was successfully incorporated into zein ultra-fine fibres at different loading amount (5%, 10% and 20%) in order to develop an encapsulating technology for functional ingredient delivery using electrospinning. The produced fibres exhibit diameters ranging from 327 to 387 nm. The physical and thermal properties of encapsulated gallic acid were determined by X-ray diffraction (XRD) and differential scanning calorimetry (DSC); and the interaction between gallic acid and zein was attested by attenuated total reflection-Fourier transform infrared (ATR-FTIR).

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