Publications by authors named "Yun Feng"

Article Synopsis
  • - RBM25 is an RNA-binding protein linked to various biological processes and has been studied for its role in tumor proliferation and metastasis, particularly in hepatocellular carcinoma (HCC) where its regulatory function is unclear.
  • - Analysis of The Cancer Genome Atlas database indicates that RBM25 is overexpressed in HCC patients compared to healthy individuals, and this overexpression correlates with poor overall survival rates, especially in male and early-stage (N0) patients.
  • - Further investigations revealed 694 genes related to RBM25, with CDCA5 and INCENP identified as key functional genes that may interact with RBM25 in regulating HCC, setting the stage for future studies on molecular pathways involved.
View Article and Find Full Text PDF

Background: Schistosomiasis japonica is a chronic parasitic disease that seriously harms people's health. Oncomelania hupensis is the only intermediate host of Schistosoma japonicum. The micro-environmental factors surrounding the snail have a great impact on the survival, growth and reproduction of O.

View Article and Find Full Text PDF

Purpose: The aim of this study was to evaluate the noninvasive diagnostic methods in managing the herpetic keratouveitis with retro-corneal endothelial plaques.

Methods: 12 patients suspected to have unilateral herpetic keratouveitis with retro-corneal endothelial plaques were included. Slit lamp photos, AS-OCT, IVCM and corneal scraping culture were taken in all cases to help diagnosing and managing the disease.

View Article and Find Full Text PDF

Oral squamous cell carcinoma (OSCC) has a high incidence of metastasis. Tumour immunotherapy targeting PD-L1 or PD-1 has been revolutionary; however, only a few patients with OSCC respond to this treatment. Therefore, it is essential to gain insights into the molecular mechanisms underlying the growth and metastasis of OSCC.

View Article and Find Full Text PDF

Background: The present study aims to provide a comparative analysis of the etiologies of female infertility between Dehong, on the Yunnan Frontier, and Kunming.

Methods: A retrospective study, which included 941 infertile females in Kunming who were treated in the First People's Hospital of Yunnan Province and infertile females who were treated in the local hospital in Dehong from January 2016 to November 2018, was conducted. A comparative analysis of the etiologies of infertility in the two regions was then carried out.

View Article and Find Full Text PDF

N6-methyladenosine (mA), one of the most prevalent RNA post-transcriptional modifications, is involved in numerous biological processes. In previous studies, the functions of mA were typically identified by perturbing the activity of the methyltransferase complex. Here, we dissect the contribution of mA to an individual-long noncoding RNA-metastasis-associated lung adenocarcinoma transcript 1 (MALAT1).

View Article and Find Full Text PDF

Fault detection for distributed parameter processes (heat processes, fluid processes, etc.) is vital for safe and efficient operation. On one hand, the existing data-driven methods neglect the evolution dynamics of the processes and cannot guarantee that they work for highly dynamic or transient processes; on the other hand, model-based methods reported so far are mostly based on the backstepping technique, which does not possess enough redundancy for fault detection since only the boundary measurement is considered.

View Article and Find Full Text PDF

Purpose: This study examined the patterned treatment of corneal collagen cross-linking (CXL) for keratoconus to reduce the complications caused by ultraviolet (UV) irradiation. By modifying the method of UV irradiation during the cross-linking process, cross-linking with a special structure is achieved, and the cross-linking effect is analyzed and compared to that of traditional cross-linking. By constructing an animal model of keratoconus, the process and effect of corneal cross-linking can be investigated more fundamentally.

View Article and Find Full Text PDF

Aims: Our study was to evaluate the benefits of human umbilical cord mesenchymal stem cells (hUCMSCs) for the prevention of premature ovarian failure (POF) in a rat model.

Materials And Methods: 80 female SD rats aged between 6 and 8 weeks were randomly divided into 4 groups A, B, C and D. Rats in group A is normal control group; group B, C and D received zona pellucida glycoprotein 3 (pZP3) administration to induce POF model.

View Article and Find Full Text PDF

Background: Recent studies have established the roles of microRNAs (miRNAs) in cancer progression. The aberrant expression of miR-335-5p has been reported in many cancers, including gastric cancer (GC). In this study, the precise roles of miR-335-5p in GC as well as the molecular mechanisms underlying its effects, including the role of its target MAPK10, were evaluated.

View Article and Find Full Text PDF

Somatic cell nuclear transfer (SCNT) holds vast potential in agriculture. However, its applications are still limited by its low efficiency. Histone 3 lysine 9 trimethylation (H3K9me3) was identified as an epigenetic barrier for this.

View Article and Find Full Text PDF

Aim: To construct a competent corneal lamellar substitute in order to alleviate the shortage of human corneal donor.

Methods: Rabbit mesenchymal stem cells (MSCs) were isolated from bone marrow and identified by flow cytometric, osteogenic and adipogenic induction. Xenogenic decellularized corneal matrix (XDCM) was generated from dog corneas.

View Article and Find Full Text PDF

Background: Genetic programs underlying preimplantation development and early lineage segregation are highly conserved across mammals. It has been suggested that nonhuman primates would be better model organisms for human embryogenesis, but a limited number of studies have investigated the monkey preimplantation development. In this study, we collect single cells from cynomolgus monkey preimplantation embryos for transcriptome profiling and compare with single-cell RNA-seq data derived from human and mouse embryos.

View Article and Find Full Text PDF

We design, fabricate and analyze plasmon-enhanced LEDs with the tapered Ag structure that significantly increases plasmonic coupling efficiency at a coupling distance far beyond the penetration depth. The electroluminescence intensity showed a 16-fold increase compared with planar LEDs with a coupling distance of 100 nm. The enhanced coupling efficiency with large distance is originated from the accumulated SP energy at the metal conical tip and the missing momentum provided by the corrugated surface.

View Article and Find Full Text PDF

Ocular drug delivery is one of the most challenging issues in ophthalmology because of the complex physiological structure of the eye. Polysaccharide-based nanomaterials have been extensively investigated in recent years as ideal carriers for enhancing the bioavailability of drugs in the ocular system because of their biocompatibility and drug solubilization. From this perspective, we discuss the structural instability of polysaccharides and its impact on the synthesis process; examine the potential for developing bioactive polysaccharide-based ocular drug nanocarriers; propose four strategies for designing novel drug delivery nanomaterials; and suggest reviewing the behavior of nanomaterials in ocular tissues.

View Article and Find Full Text PDF

Fe-modified biochars have been widely used in removal of Cr(VI) from water due to the resulting modified surface functional groups and magnetization property. However, few studies have synthetically investigated modification methods and synthesis parameters on the improvement of the removal efficiency of Cr(VI) by Fe-modified biochars. Herein, 10 types of corn straw-based magnetic biochars were produced using pre-modification and post-modification methods with various modifier ratios, and the highest heating temperature (HHT).

View Article and Find Full Text PDF

CCK8: Cell Counting Kit-8; CDK: cyclin-dependent kinase; DRD2: dopamine D2 receptor; ERK1/2: extracellular signal-regulated kinase 1/2; GAPDH: glyceraldehyde 3-phosphate dehydrogenase; H&E: hematoxylin and eosin; MMP: membrane potential; NAC: N-acetyl-L-cysteine; PI: Propidium iodide; Rh123: rhodamine-123; ROS: reactive oxygen species; TBST: tris-buffered saline containing 0.1% Tween 20 TNBC: Triple-negative breast cancer; Thi-hyd: Thioridazine hydrochloride.

View Article and Find Full Text PDF

Background: Peptide probes can be applied for biomarker targeting to improve the diagnostic accuracy. Cluster of differentiation 44 (CD44) is up-regulated in gastric cancer (GC). Among all the variants of CD44, CD44v6 is reported the most promising biomarker for GC.

View Article and Find Full Text PDF

Fluorine-containing sludge from semiconductor industries were one kind of hazardous wastes, there was hardly effective treatment to realize its safe disposal and utilization. This paper evaluated the potential of preparing cement clinker by adding the sludge into raw meal by a series of experiments. The results revealed 2.

View Article and Find Full Text PDF

This study focused on the application of functional magnetic resonance imaging and neuropsychology in diagnosis of vascular mild cognitive impairment (MCI) and the exploration of its relevant factors. The study enrolled 28 patients with vascular MCI in an observation group and 30 healthy individuals in a control group. All patients underwent magnetic resonance imaging.

View Article and Find Full Text PDF

Objective: This study aimed to quantitatively summarize the evidence for VDR BsmI gene polymorphism and osteoporosis risk in postmenopausal women.

Materials And Methods: The PubMed, EMBASE, Weipu, CNKI, and Wanfang databases were searched for eligible studies. Case-control studies containing available genotype frequencies of B/b were chosen, and odds ratio (OR) with 95% confidence interval (CI) was used to assess the strength of this association.

View Article and Find Full Text PDF

Objective: This study aimed to investigate the expression level of protein kinase D (PKD) in oral squamous cell carcinoma (OSCC) and its relationship with differentiation of OSCC.

Methods: Sample was collected from 10 healthy control subjects and 40 OSCC confirmed by histopathological diagnosis, and the immunohistochemical staining was adopted to detect the expression of PKDs in OSCC tissues. The proportion of stained cell and staining intensity were evaluated to get a score, which used to analyze the difference among PKD1, PKD2 and PKD3 in various differentiation OSCC tissues.

View Article and Find Full Text PDF

This study mainly explored the effects of Rapamycin on the growth of the Buffalo ear fibroblast (BEF) and embryonic developmental competence of somatic cell nuclear transfer (SCNT). The results show that the appropriate concentration (1 μM) of Rapamycin could significantly improve the proportion of the G0/G1 phase in BEF cells treated at a certain time (72 hr). Simultaneously, the percentage of the G0/G1 phase also was significantly higher than the serum starvation and control group.

View Article and Find Full Text PDF

Background: The impact of corticosteroid therapy on outcomes of patients with coronavirus disease 2019 (COVID-19) is highly controversial. We aimed to compare the risk of death between COVID-19-related ARDS patients with corticosteroid treatment and those without.

Methods: In this single-center retrospective observational study, patients with ARDS caused by COVID-19 between January 20, 2020, and February 24, 2020, were enrolled.

View Article and Find Full Text PDF

Coronavirus disease-2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The infection is spreading globally and poses a huge threat to human health. Besides common respiratory symptoms, some patients with COVID-19 experience gastrointestinal symptoms, such as diarrhea, nausea, vomiting, and loss of appetite.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessionm5as9dpjhionsirtspi0g5tfbk7miedo): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once