Publications by authors named "Yun Cheuk Leung"
Org Biomol Chem
January 2019
Article Synopsis
- - The study explores how stereoselective fluorination can change the properties of a cyclic tetrapeptide that contains RGD.
- - It evaluates three main outcomes: how fluorination affects the efficiency of peptide cyclization, the adjustment of molecular shape, and the influence on the biological activity of the cyclic peptides.
- - Results indicate that fluorination significantly impacts all three aspects, leading to important insights in peptide design.
Beilstein J Org Chem
November 2017
Article Synopsis
- Backbone-extended amino acids could revolutionize peptide and protein science if their structures can be controlled.
- The study focuses on creating δ-amino acids with three C-F bonds along their backbone using various synthetic methods.
- The researchers found that different diastereoisomers of these fluorinated amino acids have unique shapes in solution, making them potentially useful as customizable building blocks for peptide development.
