Publications by authors named "Yumi Hino"

Article Synopsis
  • Stiff-person syndrome is a rare autoimmune and neurogenic disorder, often linked to thymoma, a type of tumor in the thymus gland.
  • Pure red blood cell aplasia is another disorder tied to thymoma, resulting in a deficiency of red blood cells.
  • This text discusses the first known case of a patient with recurrent thymoma exhibiting both stiff-person syndrome and pure red blood cell aplasia, which improved after the tumor was surgically removed.
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Lung cancer accounts for the largest number of new cases of cancer deaths annually. The treatment of locally advanced non-small-cell lung cancer(NSCLC)will continue to be a problem for many years. In particular, the border-zone subset of stage III A(N2)patients, which lies between the generally resectable stage I and II tumors and the unresectable stage III B patients, has been the subject of a wide variety of clinical trials incorporating various combinations of chemotherapy, radiotherapy, and surgery.

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The Group-II/III WW domains bind Pro-rich sequences, the most frequent protein motif found in eucaryotic genomes. We have proposed that the Group-II and -III WW domains be merged into a larger group because the members of each group have relatively wide specificity and bind to the common ligands [Kato et al., J Biol Chem 2004;279:31833-31841].

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