Publications by authors named "Yuman Yin"
Objective: The relationship between gut microbiome and trimethylamine oxide (TMAO) has not been fully elucidated. We aimed to assess the causal effects of different gut microbes on TMAO using Mendelian randomization (MR).
Methods: Gut microbiome and TMAO datasets were acquired from genome-wide association studies and screened for single nucleotide polymorphisms according to the basic assumptions of MR.
Unequal causality between autoimmune thyroiditis and inflammatory bowel disease: a Mendelian randomization study.
Front Endocrinol (Lausanne)
November 2024
Objective: This study aims to analyze the causal relationship between autoimmune thyroiditis (AIT) and inflammatory bowel disease (IBD) using bidirectional Mendelian randomization (MR).
Methods: Single nucleotide polymorphisms were obtained from FinnGen. Exposure-outcome causality was assessed using inverse variance weighted, MR-Egger, and weighted median.
Auricular pressure as an adjuvant treatment for type 2 diabetes: data mining and meta-analysis.
Front Endocrinol (Lausanne)
September 2024
Article Synopsis
- - This study investigated the effectiveness of auricular pressure therapy combined with conventional treatments for managing type 2 diabetes, analyzing data from various databases until November 2023.
- - The results showed that patients receiving combined treatment had significantly lower levels of fasting blood glucose, postprandial blood glucose, HbA1c, cholesterol, and blood pressure compared to those only on conventional treatment, with no significant increase in adverse events.
- - Key acupoints identified for auricular pressure therapy included AH, TF, AT, CO, and CO, suggesting that this approach could be a valuable addition to diabetes care.
Objective: The role of different immune cells in autism spectrum disorders (ASD) is still controversial. The purpose of this study was to evaluate the causal effects of different immune cell phenotypes on ASD via Mendelian randomization (MR).
Methods: Datasets of immune cell phenotypes were obtained from the European Bioinformatics Institute, and datasets of ASD were obtained from the IEU Open GWAS project.
Objective: The role of esketamine in pediatric gastrointestinal endoscopy is still unclear. This study aims to evaluate the efficacy and safety of esketamine for pediatric gastrointestinal endoscopy.
Methods: Clinical trials of esketamine for pediatric gastrointestinal endoscopy were searched in eight common databases, up to October 2023.
A strategic study of acupuncture for diabetic kidney disease based on meta-analysis and data mining.
Front Endocrinol (Lausanne)
March 2024
Objective: The specific benefit and selection of acupoints in acupuncture for diabetic kidney disease (DKD) remains controversial. This study aims to explore the specific benefits and acupoints selection of acupuncture for DKD through meta-analysis and data mining.
Methods: Clinical trials of acupuncture for DKD were searched in eight common databases.
Effect of tea intake on genetic predisposition to gout and uric acid: a Mendelian randomization study.
Front Endocrinol (Lausanne)
March 2024
Objective: The effect of tea on gout and uric acid is still controversial. This study aims to analyze the effect of tea intake on genetic predisposition to gout, idiopathic gout, gout due to impairment of renal function as well as uric acid by Mendelian randomization (MR).
Methods: Forty independent single nucleotide polymorphisms (SNPs) associated with tea intake were selected from UK Biobank.
Objective: The efficacy of acupoint catgut embedding (ACE) for the treatment of pre-diabetes remains controversial. Therefore, this study investigated the clinical efficacy and acupoint selection in ACE for the treatment of pre-diabetes.
Methods: Eight common databases were searched for relevant literature on ACE for pre-diabetes.