Publications by authors named "Yuma Miyake"
Environ Int
February 2023
Article Synopsis
- Exposure to plastic-related endocrine disrupting chemicals (EDCs), like phthalates, is linked to chronic health risks and significant societal costs, with evidence of increased cardiometabolic issues in mouse models.
- Paternal exposure to a specific phthalate, dicyclohexyl phthalate (DCHP), was found to negatively impact the metabolic health of subsequent generations, particularly influencing insulin resistance and leading to sex-specific health challenges in female descendants.
- The study highlights that changes in sperm small non-coding RNAs due to DCHP exposure may play a role in transmitting these adverse metabolic effects across generations, providing new insight into how chemical exposure contributes to chronic diseases.
