Development and characterization of a modified Komarov's bullet for ballistic delivery of live Brucella abortus strains 82 and 19 to cattle and bison.

In this study a modified Komarov's bullet was developed to remotely deliver live brucellosis vaccines (Brucella abortus 82 and Brucella abortus 19). After modification, the bullet payload could carry the desired dose (10(11)CFU) of vaccine. As the bullet components were toxic to the live bacteria, a special protective coating was developed for the bullet inner surface that maintained vaccine viability.