Macrophage MST1 protects against schistosomiasis-induced liver fibrosis by promoting the PPARγ-CD36 pathway and suppressing NF-κB signaling.

Schistosomiasis is characterized by egg-induced hepatic granulomas and subsequent fibrosis. Monocyte-derived macrophages play critical and plastic roles in the progression and regression of liver fibrosis, adopting different polarization phenotypes. Mammalian STE20-like protein kinase 1 (MST1), a serine/threonine kinase, has been established to act as a negative regulator of macrophage-associated inflammation.

Enhancing the Performance of Perovskite Light-Emitting Diodes via Synergistic Effect of Defect Passivation and Dielectric Screening.

Metal halide perovskites, particularly the quasi-two-dimensional perovskite subclass, have exhibited considerable potential for next-generation electroluminescent materials for lighting and display. Nevertheless, the presence of defects within these perovskites has a substantial influence on the emission efficiency and durability of the devices. In this study, we revealed a synergistic passivation mechanism on perovskite films by using a dual-functional compound of potassium bromide.

Acceleration of radiative recombination for efficient perovskite LEDs.

The increasing demands for more efficient and brighter thin-film light-emitting diodes (LEDs) in flat-panel display and solid-state lighting applications have promoted research into three-dimensional (3D) perovskites. These materials exhibit high charge mobilities and low quantum efficiency droop, making them promising candidates for achieving efficient LEDs with enhanced brightness. To improve the efficiency of LEDs, it is crucial to minimize nonradiative recombination while promoting radiative recombination.

Fault Diagnosis Method for Rolling Bearings Based on Grey Relation Degree.

Aiming at the difficult problem of extracting fault characteristics and the low accuracy of fault diagnosis throughout the full life cycle of rolling bearings, a fault diagnosis method for rolling bearings based on grey relation degree is proposed in this paper. Firstly, the subtraction-average-based optimizer is used to optimize the parameters of the variational mode decomposition algorithm. Secondly, the vibration signals of bearings are decomposed by using the optimized results, and the feature vector of the intrinsic mode function component corresponding to the minimum envelope entropy is extracted.

A Preliminary Study of the Impacts of Duckweed Coverage during Rice Growth on Grain Yield and Quality.

The overuse and misuse of fertilizers have been causing duckweed outbreaks in irrigation ditches and paddy fields in many rice-growing areas. However, how duckweed coverage in a paddy field affects the rice yield and grain quality is under debate because duckweed may act as either a weed, competing with rice for mineral nutrients, or a "nutrient buffer", providing significant ecological and economic benefits. To understand the effects of duckweed coverage throughout rice growth on the yield and quality of rice grains, an experiment with three rice cultivars was conducted with fertile lotus-pond bottom soil as a growth medium to provide sufficient mineral nutrients for both the duckweed and rice.

Persistent Charging of CsPbBr Perovskite Nanocrystals Confined in Glass Matrix.

Manipulation of persistent charges in semiconductor nanostructure is the key point to obtain quantum bits towards the application of quantum memory and information devices. However, realizing persistent charge storage in semiconductor nano-systems is still very challenge due to the disturbance from crystal defects and environment conditions. Herein, the two-photon persistent charging induced long-lasting afterglow and charged exciton formation are observed in CsPbBr perovskite nanocrystals (NCs) confined in glass host with effective lifetime surpassing one second, where the glass inclosure provides effective protection.

Layered energy-saving speed planning and control method for electric vehicle on continuous signal lights road.

Emergency start-stop in front of signal lights is one of the main reasons for additional energy consumption and ride discomfort of Electric Vehicle (EV). Existing research on this issue rarely takes into account both energy consumption and ride comfort. Therefore, the layered energy-saving speed planning and control method is proposed.

Passivating Defects at the Bottom Interface of Perovskite by Ethylammonium to Improve the Performance of Perovskite Solar Cells.

The interface of perovskite solar cells (PSCs) plays a significant role in influencing their performance, yet there is still scarce research focusing on their difficult-to-expose bottom interfaces. Herein, ethylammonium bromide (EABr) is introduced into the bottom interface and its passivation effects are studied directly. First, EABr can improve substrate wettability, which is beneficial for the perovskite-film deposition.

Traditional Chinese Medicine Formula Jian Pi Tiao Gan Yin Reduces Obesity in Mice by Modulating the Gut Microbiota and Fecal Metabolism.

The current study employed the high-fat diet (HFD) induced murine model to assess the relationship between the effect of Jian Pi Tiao Gan Yin (JPTGY) and the alterations of gut microbiota and fecal metabolism. C57BL/6 mice were used to establish an animal model of obesity via HFD induce. Serum biochemical indicators of lipid metabolism were used to evaluate the pharmacodynamics of JPTGY in obese mice.

High-Yield Production of Lignin-Derived Functional Carbon Nanosheet for Dye Adsorption.

In this article, we report the preparation of lignin-derived carbon nanosheet (L-CNS) by direct thermal treatment of lignin without activation operation and the functions of the L-CNS as an adsorbent for rhodamine dye. The L-CNSs are fabricated by freeze-drying (FD) methods of lignin followed by high-temperature carbonization. It is found that lower frozen temperature in FD or lower concentration of lignin aqueous solution renders L-CNSs' more porous morphology and higher specific surface area (SSA), allowing a promising application of the L-CNSs as an efficient adsorbent for organic pollutants.

Catalytic Activity of Ag-Co-MCM-41 for Liquid-Phase Selective Oxidation of Styrene to Benzaldehyde.

A series of Ag-Co-MCM-41 with different metal loadings have been synthesized through the hydrothermal method. All the prepared catalysts were characterized by N₂ adsorption-desorption, X-ray diffraction analysis, transmission electron microscopy. The results revealed that the structure of MCM-41 was well preserved and Ag and Co have been introduced successfully into the mesoporous channels of MCM-41.

[Clinical Observation of the Proprioceptive Sensibility Reflexotherapy by Tendon Acupuncture at Trigger Points for Cervical Vertigo].

Objective: To evaluate the efficacy of the proprioceptive sensibility reflexotherapy by tendon acupuncture needling at trigger points for patients with proprioceptive disorder of cervical vertigo.

Methods: Seventy-nine patients with proprioceptive disorder of cervical vertigo were randomly assigned into a treatment group (42 cases) and a control group (37 cases). Patients in the treatment group received the proprioceptive sensibility reflexotherapy with tendon acupuncture at trigger points in the neck.

Sub-pm linewidth nanosecond Nd:GYSGG laser at 1336.6 nm.

We demonstrate a sub-pm linewidth acousto-optic (AO) Q-switched nanosecond Nd:GYSGG ring laser at 1336.6 nm side-pumped by 808-nm quasi-continuous wave (QCW) diode lasers for the first time. With incident pulse energy of 4.