Case Report: Cranial Tuberculosis in a Patient without Tuberculosis Foci Elsewhere in the Body.

Cranial tuberculosis is a relatively infrequent inflammatory reaction caused by tuberculous bacilli invading the skull. Most cases of cranial tuberculosis are secondary to tuberculosis foci in other parts of the body; primary cranial tuberculosis is extremely rare. Herein, we report a case of primary cranial tuberculosis.

The therapeutic effect of an autologous and allogenic mixed glioma cell lysate vaccine in a rat model.

Purpose: Tumor immunotherapy has the advantages of high specificity, minimal damage to the patient's body, and a long-lasting anti-tumor effect. However, due to the existence of immune escape phenomenon, the effect of anti-tumor immunotherapy is still poor. Therefore, a cancer vaccine that reverses tumor-associated immunosuppression is a very promising approach for research and treatment.

Elevated RECQL1 expression predicts poor prognosis and associates with tumor immune infiltration in low-grade glioma.

Background: Dysregulation of RecQ protein-like 1 (RECQL1), a member of the RecQ DNA helicase, has been determined to participate in malignant process of numerous tumors such as immunosuppression and proliferation and may serve as a biomarker for certain malignancies. Nevertheless, whether there is a similar association between RECQL1 and low-grade glioma (LGG) is uncertain. We therefore turned our attention to exploring the association of RECQL1 with tumor immune infiltration and prognostic significance in LGG.