Effects of BMI and grip strength on older adults' falls-A longitudinal study based on CHARLS.

Background: Body Mass Index (BMI) and grip strength are potentially important risk factors for falls among the older adults. Currently, there is no consensus on the combined effects of grip strength and BMI on falls in the older adults, particularly among the Chinese older adults.

Objective: To investigate the incidence of falls among older adults in China and explore the association between BMI and grip strength and the risk of falls in older adults.

Associations of the implementation of the three-child policy with changes in contraceptive methods among women who underwent induced abortion: a cross-sectional study of Wuhan, a megacity in central China.

Background: Induced abortion, as a legal medical practice in China, has an enormous negative impact on women's sexual and reproductive health. After the implementation of the three-child policy, guiding women to choose appropriate contraceptive measures to protect their fertility is the focus of China's family planning. But little is known about the impact of the family planning policy on women's contraceptive behaviour.

Dietary patterns and metabolic syndrome amongst adult residents: A cross-sectional study in a rapidly urbanized Southern Chinese city.

We aimed to investigate and summarize dietary patterns and explore the association between dietary patterns and metabolic syndrome (MS) and its components among adult residents in a rapidly urbanized city. We employed a multi-stage random sampling method to select 1000 adult residents who underwent a comprehensive survey, including questionnaires, physical examinations, and laboratory tests. The diagnosis of metabolic syndrome was made when the participant met 3 or more of the 5 criteria outlined in the "2017 Chinese Guidelines for the Prevention and Treatment of Type 2 diabetes.

Kinetic study on anaerobic digestion of long-chain fatty acid enhanced by activated carbon adsorption and direct interspecies electron transfer.

This study applied granular activated carbon (GAC) to improve the anaerobic digestion of long-chain fatty acid (LCFA). New kinetics were considered to describe the effect of GAC on the LCFA degradation, including i) The adsorption kinetics of GAC for LCFA, ii) The β-oxidation pathway of LCFA, iii) The attached biomass improved by direct interspecies electron transfer (DIET). The developed model simulated the anaerobic digestion of stearic acid, palmitic acid, myristic acid, and lauric acid with 1.

Unveiling moisture transport mechanisms in cellulosic materials: Vapor vs. bound water.

Natural textiles, hair, paper, wool, or bio-based walls possess the remarkable ability to store humidity from sweat or the environment through "bound water" absorption within nanopores, constituting up to 30% of their dry mass. The knowledge of the induced water transfers is pivotal for advancing industrial processes and sustainable practices in various fields such as wood drying, paper production and use, moisture transfers in clothes or hair, humidity regulation of bio-based construction materials, etc. However, the transport and storage mechanisms of this moisture remain poorly understood, with modeling often relying on an assumption of dominant vapor transport with an unknown diffusion coefficient.

Critical Role of Boundary Conditions in Sorption Kinetics Measurements.

In order to characterize the hygroscopic properties of cellulose-based materials, which can absorb large amounts of water from vapor in ambient air, or the adsorption capacity of pollutants or molecules in various porous materials, it is common to rely on sorption-desorption dynamic tests. This consists of observing the mass variation over time when the sample is placed in contact with a fluid containing the elements to be absorbed or adsorbed. Here, we focus on the case of a hygroscopic material in contact with air at a relative humidity (RH) differing from that at which it has been prepared.

Parental Support Is Associated with Moderate to Vigorous Physical Activity among Chinese Adolescents through the Availability of Physical Activity Resources in the Home Environment and Autonomous Motivation.

This study aimed to use a structural equation model (SEM) to determine the association between parental support and moderate to vigorous physical activity (MVPA) among Chinese adolescents and whether the availability of physical activity (PA) resources in the home environment and autonomous motivation of adolescents mediated the association. Data were collected using questionnaires extracted from the Family Life, Activity, Sun, Health, and Eating (FLASHE) study. A final analytical sample of 3738 adolescents was enrolled.

Hypermethylated and in Cytological Specimens as Screening Biomarkers for Endometrial Cancer.

We aimed to estimate the diagnostic value of DNA methylation levels in cytological samples of endometrial cancer (EC) and atypical hyperplasia (AH). Two hypermethylated genes, namely, cysteine dioxygenase type 1 () and zinc finger protein 454 (), in patients with EC were identified from The Cancer Genome Atlas database. In 103 endometrial histological specimens (the training set), the methylation levels of candidate genes were verified by quantitative methylation-specific polymerase chain reaction (qMSP).

An Effective Protocol for Management of International Arrivals at Risk in COVID-19 Pandemic: Experience From the Pre-Hospital Covid-19 Response Teams at Xi'an, China.

Background: The coronavirus disease 2019 (COVID-19) outbreak within China has been well controlled and stabilized since early April 2020. Therefore, the current major focus in China is to prevent the introduction of COVID into China from international arrivals. To achieve this, pre-Hospital COVID-19 Response Teams (pHCRTs) have been established.

Sanguinarine Reverses Pulmonary Vascular Remolding of Hypoxia-Induced PH Survivin/HIF1α-Attenuating Kv Channels.

Similarities in the biology of pulmonary hypertension and cancer suggest that anticancer therapies, such as sanguinarine, may also be effective in treating pulmonary hypertension. This, along with underlying biochemical pathways, is investigated in this study. Rats were subjected to 4-week hypoxia (or control) with or without sanguinarine treatment.

Acute Effects of Air Pollution on Ischemic Heart Disease Hospitalizations: A Population-Based Time-Series Study in Wuhan, China, 2017-2018.

Evidence of the acute effects of air pollutants on ischemic heart disease (IHD) hospitalizations based on the entire population of a megacity in central China is lacking. All IHD hospitalization records from 2017 to 2018 were obtained from the Wuhan Information Center of Health and Family Planning. Daily air pollutant concentrations and meteorological data were synchronously collected from the Wuhan Environmental Protection Bureau.

A Systematic Review and Meta-Analysis of the Prognostic Impact of Pretreatment Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Parameters in Patients with Locally Advanced Cervical Cancer Treated with Concomitant Chemoradiotherapy.

Backgrounds: The purpose of this paper is to investigate the prognostic value of fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) parameters in patients treated with concurrent chemoradiotherapy (CCRT) for locally advanced cervical cancer (LACC).

Methods: Studies that met the following criteria were retrieved from PubMed and Embase: patients treated with CCRT for LACC; FDG PET/CT scans performed before CCRT treatment; and a detected relationship between the parameters of FDG PET/CT and the prognosis of patients. Pooled hazard ratios (HRs) with 95% confidence intervals (CIs) were used to estimate the overall survival (OS) or event-free survival (EFS).

Effect of different initial anticoagulant strategies on short-term outcome of patients with symptomatic DVT in China.

Purpose: In ambulant patients with lower limb DVT managed with Warfarin, there is a need for initial treatment and short time "bridging" with a rapidly acting anticoagulant until there is a stable therapeutic INR. In this study, results from bridging with subcutaneous low molecular weight heparin (LMWH) or oral Rivaroxaban were compared.

Methods: One hundred and twenty-four patients received LMWH and 98 patients received Rivaroxaban, both in addition to Warfarin.

Built environment, physical activity, and obesity of adults in Pingshan District, Shenzhen City in Southern China.

Background: The relation between neighbourhood built environment and obesity has been described as both nuanced and complex.

Aim: The objective of this study was to examine the relationship between the built environment, physical activity, and obesity in a rapidly urbanised area of China.

Subjects And Methods: This is a cross-sectional study.

Detection of carcinoma in serous effusions: a review.

A malignant serous effusion is one of the most common complications of advanced tumors, indicating a poor prognosis and having a profound impact on diagnosis, treatment, and prognosis. It is of great significance to identify benign and malignant effusions quickly and accurately. Both cellular and non-cellular components in the effusion can be employed for detection, diagnostic methods are necessary to obtain a definite diagnosis and more relevant information such as tumor classification.

Association between intake of white rice and incident type 2 diabetes - An updated meta-analysis.

Aims: Meta-analyses on the association between white rice intake and incident type 2 diabetes (T2D) have been inconsistent. Since the last meta-analysis, more studies have been published with inconsistent results. We aimed to examine the rice-T2D association in Asian populations in an updated meta-analysis.

Berberine inhibits the Warburg effect through TET3/miR-145/HK2 pathways in ovarian cancer cells.

Berberine, as an alkaloid, has a significant antitumor effect, but its mechanism in tumor metabolism, especially the Warburg effect has not been elucidated. To study the molecular mechanism of berberine regulating the Warburg effect in ovarian cancer cells. Treatment by berberine in SKOV3 and 3AO cells or inhibited by miR-145 inhibitor transfection in berberine-treated cells to examine the changes in HK2 expression, glucose consumption and lactate production.

Associating COVID-19 Severity with Urban Factors: A Case Study of Wuhan.

Wuhan encountered a serious attack in the first round of the coronavirus disease 2019 (COVID-19) pandemic, which has resulted in a public health social impact, including public mental health. Based on the Weibo help data, we inferred the spatial distribution pattern of the epidemic situation and its impacts. Seven urban factors, i.

Comparison of Cervical Cytopathological Diagnosis Using Innovative Qi Brush and Traditional Cervex-Brush® Combi.

To compare the effectiveness between Qi brush and Cervex-Brush® Combi for the diagnosis of cervical lesions. After we registered a random-control clinical trial on the Chinese Clinical Trial Registry (No. XJTU1AF2017LSK-25), cervical cell samples were successively collected with both Qi brush and Cervex-Brush® Combi before undergoing colposcope.

The association between ambient temperature and sperm quality in Wuhan, China.

Background: Few epidemiological investigations have focused on the influence of environmental temperature on human sperm quality. Here, we evaluated the potential association between ambient temperature and human sperm quality in Wuhan, China, and examined the interactive effect of particulate matter (PM) and temperature.

Methods: 1780 males who had been living in Wuhan for no less than three months and received semen analysis at the Department of Reproductive Medicine in Renmin Hospital of Wuhan University between April 8, 2013 and June 30, 2015 were recruited.

What is global health? Key concepts and clarification of misperceptions: Report of the 2019 GHRP editorial meeting.

The call for "W requires us to improve people's health across the globe, while global health development entails a satisfactory answer to a fundamental question: "What is global health?" To promote research, teaching, policymaking, and practice in global health, we summarize the main points on the definition of global health from the Editorial Board Meeting of Global Health Research and Policy, convened in July 2019 in Wuhan, China. The meeting functioned as a platform for free brainstorming, in-depth discussion, and post-meeting synthesizing. Through the meeting, we have reached a consensus that global health can be considered as a general guiding principle, an organizing framework for thinking and action, a new branch of sciences and specialized discipline in the large family of public health and medicine.

Neighbourhood built environment and leisure-time physical activity: A cross-sectional study in southern China.

This study conducted scientific evidence linking neighbourhood built environment to adults' leisure-time physical activity (LTPA) among adults in China. Data were obtained from a questionnaire survey conducted from April to July 2017 among 1002 adults aged 18-69 years old in Pingshan District, Shenzhen, China. Chinese Walkable Environment Scale for urban community residents and International Physical Activity Questionnaire were used to measure participants' neighbourhood built environment and leisure-time physical activity, which was categorised into leisure-time walking (LTW) and leisure-time moderate-to-vigorous physical activity (LTMVPA).

miR-145 promotes miR-133b expression through c-myc and DNMT3A-mediated methylation in ovarian cancer cells.

Ovarian cancer presents as malignant tumors in the female reproductive system with high mortality. MicroRNAs are involved in the progression of ovarian cancer; however, the regulatory relationship among miRs remains unclear. In our study, we verified that both miR-145 and miR-133b messenger RNA (mRNA) levels in ovarian cancer tissues were lower than in normal ovarian tissues, and their mRNA level in serum of patients with ovarian cancer was reduced.