Publications by authors named "Yulia V Fomicheva"
Article Synopsis
- This study investigates the genetic underpinnings of neuroendocrine tumors (NETs) by using targeted gene panels (TGPs) to identify novel genetic variants in a group of 93 patients with different NET subtypes.
- Out of the identified variants, some were already known to be linked to specific tumor types, while others were new associations that had not been previously recognized in the context of NETs.
- The research highlights the potential of TGPs to uncover previously unknown genetic factors in NET development, suggesting the need for further studies with larger samples to confirm these findings.
Genetic variants in gene were identified in patients with various arrhythmogenic conditions including Brugada syndrome. Despite significant progress of last decades in studying the molecular mechanism of arrhythmia-associated mutations, the understanding of relationship between genetics, electrophysiological consequences and clinical phenotype is lacking. We have found a novel genetic variant Y739D in the encoded sodium channel Na1.
View Article and Find Full Text PDFPericardial fluid is enriched with biologically active molecules of cardiovascular origin including microRNAs. Investigation of the disease-specific extracellular microRNAs could shed light on the molecular processes underlying disease development. Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart disease characterized by life-threatening arrhythmias and progressive heart failure development.
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