Publications by authors named "Yuli Liang"
Article Synopsis
- A clinical trial was conducted to compare gene-based dosing of 6-mercaptopurine (6-MP) to standard dosing in Chinese children with acute lymphoblastic leukemia (ALL), focusing on those with low- or intermediate-risk.
- The gene-based dosing resulted in a 2.2-fold decrease in myelosuppression compared to standard dosing, using approximately half the standard dose, and significantly reduced the risk of leukopenia.
- No major differences were found in hepatotoxicity or metabolite concentrations in the blood between the two treatment groups, suggesting that gene-based dosing may be a safer alternative for this patient population.
Chronic obstructive pulmonary disease is the 3rd leading cause of death worldwide, and the available treatments are unsatisfactory, resulting in a major economic burden. As cellular therapy is commonly used for lung disease, we investigated a treatment with CXCR4-overexpressing BMSCs in a COPD model. We extracted and purified Bone marrow mesenchymal stem cells (BMSCs) from SD rats.
View Article and Find Full Text PDFObjectives: This study psychometrically evaluated General Self-Efficacy (GSE) Scale in patients planned for bariatric surgery in Sweden.
Design: A cross-sectional psychometric study. The psychometric evaluation was guided by the COnsensus-based Standards for the selection of health status Measurement Instruments checklist for health-related reported-patient outcomes.
Article Synopsis
- This article explores simultaneous hypothesis testing for mean and covariance matrix in repeated measures data, focusing on scenarios where both are patterned.
- It specifically examines tests for the mean vector using block circular and doubly exchangeable covariance structures.
- The authors establish null distributions for likelihood ratio test statistics and provide both probability density and cumulative distribution functions, supported by simulations and a real-world example.
Objectives: The aim was to psychometrically test and evaluate the Swedish functional health literacy scale and the Swedish communicative and critical health literacy scale in patients undergoing bariatric surgery.
Design: A prospective cross-sectional psychometric study.
Setting: Patients from three bariatric centres in Sweden were consecutively included in this study.
To investigate the effects of a novel synthetic epidermal growth factor receptor inhibitor, COMPOUND7809, on the inhibition of lung cancer growth in vitro and the underlying mechanisms, we treated three lung tumor cell lines (A549, SK-LU-1, and NCI-H23) with COMPOUND7809 and a Food and Drug Administration-approved epidermal growth factor receptor inhibitor gefitinib. Then, we examined cell growth in a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay, cell survival in a Cell Counting Kit-8 assay, and cell apoptosis by Annexin V flow cytometry in the presence of fluorouracil. We found that compared to gefitinib, COMPOUND7809 inhibited cell growth more potentially and induced more cell death in the presence of fluorouracil.
View Article and Find Full Text PDFConflicting results were implicated in both single case-control studies and meta-analyses of the correlation between p73 G4C14-to-A4T14 polymorphism and lung cancer risk. We designed this study to further assess the association by meta-analysis. A meta-analysis was performed based on five case-control studies (5,467 subjects) retrieved from PubMed and Embase.
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