Advances in Repetitive Transcranial Magnetic Stimulation for the Treatment of Post-traumatic Stress Disorder.

Post-traumatic stress disorder (PTSD) is a psychiatric disorder that develops and persists after an individual experiences a major traumatic or life-threatening event. While pharmacological treatment and psychological interventions can alleviate some symptoms, pharmacotherapy is time-consuming with low patient compliance, and psychological interventions are costly. Repetitive Transcranial Magnetic Stimulation (rTMS) is a safe and effective technique for treating PTSD, with advantages such as high compliance, low cost, and simplicity of implementation.

A multi-scenario ensemble approach incorporating stepwise cluster analysis to reduce uncertainty in large-scale watershed precipitation projections: a case study of Pearl River Basin, South China.

Assessing and selecting climate models with lower uncertainty is necessary to predict future climate and hydrological risks at the watershed scale. In this study, we integrated stepwise cluster analysis (SCA) to propose a multi-model ensemble downscaling framework aimed at reducing the uncertainty of GCM-based precipitation projections in large-scale watersheds. The Pearl River Basin (PRB) in southern China was selected as the study area to validate the reliability of this framework.

Exploration of resting-state brain functional connectivity as preclinical markers for arousal prediction in prolonged disorders of consciousness: A pilot study based on functional near-infrared spectroscopy.

Background: There is no diagnostic assessment procedure with moderate or strong evidence of use, and evidence for current means of treating prolonged disorders of consciousness (pDOC) is sparse. This may be related to the fact that the mechanisms of pDOC have not been studied deeply enough and are not clear enough. Therefore, the aim of this study was to explore the mechanism of pDOC using functional near-infrared spectroscopy (fNIRS) to provide a basis for the treatment of pDOC, as well as to explore preclinical markers for determining the arousal of pDOC patients.

Development and validation of a nomogram for predicting heterotopic ossification following spinal cord injury.

Objective: Heterotopic ossification (HO) following spinal cord injury (SCI) can severely compromise patient mobility and quality of life. Precise identification of SCI patients at an elevated risk for HO is crucial for implementing early clinical interventions. While the literature presents diverse correlations between HO onset and purported risk factors, the development of a predictive model to quantify these risks is likely to bolster preventive approaches.

Systemic immune-inflammation index as a novel predictor of major adverse cardiovascular events in patients undergoing percutaneous coronary intervention: a meta-analysis of cohort studies.

Background: The Systemic Immune-Inflammation Index (SII), a novel marker of inflammation based on neutrophil, platelet, and lymphocyte counts, has demonstrated potential prognostic value in patients undergoing percutaneous coronary intervention (PCI). Our aim was to assess the correlation between the SII and major adverse cardiovascular events following percutaneous coronary intervention.

Methods: We searched PubMed, Web of Science, Embase, and The Cochrane Library from inception to November 20, 2023, for cohort studies investigating the association between SII and the occurrence of MACEs after PCI.

A unified deep learning framework for water quality prediction based on time-frequency feature extraction and data feature enhancement.

Deep learning methods exhibited significant advantages in mapping highly nonlinear relationships with acceptable computational speed, and have been widely used to predict water quality. However, various model selection and construction methods resulted in differences in prediction accuracy and performance. Hence, a unified deep learning framework for water quality prediction was established in the paper, including data processing module, feature enhancement module, and data prediction module.

Regional bioethanol supply chain optimization with the integration of GIS-MCDM method and quantile-based scenario analysis.

This study presents a novel decision-support framework for the bioethanol supply chain network planning and management under uncertainties. Under the holistic framework, the most suitable sites for biorefineries are first screened out by adopting a GIS-based multi-criteria decision-making approach. Then, a mixed-integer linear programming model combined with quantile-based scenario analysis is developed to determine the strategic planning (i.

Different policies constrained agricultural non-point pollutants emission trading management for water system under interval, fuzzy, and stochastic information.

Formulating suitable policies is essential for resources and environmental management. In this study, an agricultural pollutants emission trading management model driven by water resources and pollutants control is developed to search reasonable policies for agricultural water resources allocation under multiple uncertainties. Random-fuzzy and interval information in water resources system that have directly impact on the effectiveness of management schemes is reflected through interval two-stage stochastic fuzzy-probability programming.

Survival nomogram for osteosarcoma patients: SEER data retrospective analysis with external validation.

This study aimed to develop a nomogram based on the clinicopathological factors affecting the prognosis of osteosarcoma patients to help clinicians predict the overall survival of osteosarcoma patients. A total of 1362 patients diagnosed with osteosarcoma were enrolled in this study, among which, 1081 cases were enrolled from the SEER (Surveillance, Epidemiology, and End Results) database as training group, while 281 patients from two Clinical Medicine Center database were used in validation group. Univariate and multivariate Cox analyses were performed to identify the independent prognostic factors for overall survival.

Source or sink role of an urban lake for microplastics from Guangdong-Hong Kong-Macao greater bay area, China.

Plastic production and consumption in China are larger than others in the world, and the challenge of microplastic pollution is widespread. With the development of urbanization in the Guangdong-Hong Kong-Macao Greater Bay Area, China, the environmental pollution of microplastics is becoming an increasingly prominent issue. Here, the spatial and temporal distribution characteristics, sources, and ecological risks of microplastics were analyzed in water from an urban lake, Xinghu Lake, as well as the contribution of rivers.

Dynamic characteristics of microplastics under tidal influence and potential indirect monitoring methods.

Rivers are an important channel for the transport of microplastics from inland areas to the ocean. It is of great significance to explore the dynamic changes in microplastic pollution characteristics under tidal fluctuations to understand the exchange of microplastics between rivers and oceans. In this study, the occurrence of microplastics in typical tidal channels in the lower reaches of the Dong River was investigated during the wet and dry weather seasons, and high frequency continuous dynamic monitoring of microplastics was carried out in a typical tidal cross section during a tidal cycle.

Prism adaptation combined with eye movement training for unilateral spatial neglect after stroke: Study protocol for a single-blind prospective, randomized controlled trial.

Background: Unilateral spatial neglect (USN) is a complex neurological syndrome that often reduces rehabilitation outcomes, prolongs patients' hospital stays, and decreases their quality of life. However, the current therapies for USN have varying efficacy. We will explore a new treatment option that combines prism adaptation (PA) with eye movement training (EMT) for the treatment of USN after stroke.

Can platelet-rich plasma enhance the effect of meniscus repair? A meta-analysis of randomized controlled trials Platelet-rich plasma and meniscus repair.

Background: Studies have shown that platelet-rich plasma (PRP) can enhance the effect of meniscus repair, but some studies have suggested different views on the role of PRP.

Purpose: To determine whether PRP can enhance the effect of meniscus repair with respect to pain reduction and improved functionality and cure rate in patients with meniscus injury.

Methods: By searching PubMed, EMBASE, Cochrane Library databases, clinicaltrials.

Preliminary Study of Vagus Nerve Magnetic Modulation in Patients with Prolonged Disorders of Consciousness.

Background: The number of patients with prolonged disorders of consciousness (pDOC) is increasing. However, its clinical treatment remains challenging. To date, no studies have reported the effect of vagus nerve modulation (VNM) using repetitive transcranial magnetic stimulation (rTMS) in patients with pDOC.

Towards low-carbon domestic circulation: Insights from the spatiotemporal variations and socioeconomic determinants of emissions embedded within cross-province trade in China.

For a country like China with unbalanced development pattern among provinces, domestic circulation (i.e., cross-province trade) is important for the long-term stability and prosperous development of economic market.

Potential Life-Cycle Environmental Impacts of the COVID-19 Nucleic Acid Test.

Massive diagnostic testing has been performed for appropriate screening and identification of COVID-19 cases in the ongoing global pandemic. However, the environmental impacts of COVID-19 diagnostics have been least considered. In this paper, the environmental impacts of the COVID-19 nucleic acid diagnostics were assessed by following a full cradle-to-grave life-cycle approach.

Changes of vegetational cover and the induced impacts on hydrological processes under climate change for a high-diversity watershed of south China.

Understanding the changes in hydrological process is a key subject for water resource management of a high-diversity watershed. In this paper, through an establishment of a SWAT-based model, the effects of climate change and its induced vegetation change on hydrological process were analyzed in the East River Basin. The model could well simulate the hydrological processes of the basin including surface runoff (SURQ), groundwater (GWQ), lateral flow (LATQ), total water yield (WYLD), actual evapotranspiration (ET), and groundwater recharge (PERC).

Analysis of Hypoxia Inducible Factor-1α Expression and Its Effects on Glycolysis of Esophageal Carcinoma.

We investigated the regulatory effects of hypoxia-inducible factor-1a (HIF-1α) on glycolysis metabolism in esophageal carcinoma (ESCA) cells. A series of bioinformatics databases and tools were used to investigate the expression and role of HIF-1α in ESCA. The expression of HIF-1a in ESCA tissues and adjacent tissues was validated by real-time PCR.

Brain-machine interface-based training for improving upper extremity function after stroke: A meta-analysis of randomized controlled trials.

Background: Upper extremity dysfunction after stroke is an urgent clinical problem that greatly affects patients' daily life and reduces their quality of life. As an emerging rehabilitation method, brain-machine interface (BMI)-based training can extract brain signals and provide feedback to form a closed-loop rehabilitation, which is currently being studied for functional restoration after stroke. However, there is no reliable medical evidence to support the effect of BMI-based training on upper extremity function after stroke.

Effect of platelet-rich plasma on meniscus repair surgery: A meta-analysis of randomized controlled trials.

Background: Studies have shown that platelet-rich plasma (PRP) can enhance the effect of meniscus repair, but some studies have suggested different views on the role of PRP. Therefore, a meta-analysis was conducted to determine whether PRP can enhance the effect of meniscus repair with respect to pain reduction and improved functionality and cure rate in patients with meniscus injury.

Methods: PubMed, EMBASE, Cochrane Library Databases, clinicaltrials.

Water-carbon nexus relationship and interaction mechanism analysis within Beijing-Tianjin-Hebei urban agglomeration.

As the total water resources consumption control and carbon mitigation continuous improvement, the weak water-carbon incorporate management is increasingly exposed. In this study, a water-carbon nexus assessment framework is proposed to analyze the nexus relationship between water consumption and carbon emission, and distinguishes the coupled water-carbon transmission intensity and the transfer paths under regional and industrial scales. According to the practical input-output table, water consumption, and carbon emission information, the framework is applied to Beijing-Tianjin-Hebei urban agglomeration (BTHUA), a population, resource, and trade intensive area of China.

Dual risk-aversion programming for regional industrial structure adjustment with water-energy nexus: A case study of Tianjin, China.

The water-energy nexus (WEN) system is a large-scale complex system that comes with diverse forms of risks owing to many challenges in the process of maintaining economic-resource-environmental sustainability. First, the rapidly increasing demand for water and energy subjects many regions to the high risk of water and energy shortages. Second, decision makers face difficulties in weighing system benefits and loss risks under a series of stricter water-energy policies.

Comparison of the effects of autologous and allogeneic purified platelet-rich plasma on cartilage damage in a rabbit model of knee osteoarthritis.

Background: Purified platelet-rich plasma (P-PRP) is gradually being used in the treatment of osteoarthritis (OA), and its sources are mainly divided into autologous and allogeneic blood. However, it is unclear whether autologous PRP is more effective or allogeneic PRP is superior.

Objective: In this study, autologous and allogeneic P-PRP was injected at early stage of KOA in rabbits, and then the differences in the efficacy of the two P-PRPs against KOA were compared from several perspectives, including pathological histology and immunohistochemistry.