Publications by authors named "Yulduz Rakibova"
Article Synopsis
- Cholera-causing bacteria utilize horizontally acquired elements (HAEs) that enhance their virulence and fitness, making them a persistent health threat.
- New strains regularly emerge with improved traits, necessitating effective regulation of these genetic elements for survival in various environments.
- Research reveals that the protein H-NS regulates HAEs by silencing excess gene expression, while another protein, TsrA, influences virulence by modulating H-NS activity, showing complex interactions between nucleoid-associated proteins in these pathogens.
Article Synopsis
- Cholera, caused by the bacterium Vibrio cholerae, poses a health threat due to its evolving genetic elements and virulence factors.
- New clinical isolates of this pathogen exhibit improved survival skills linked to horizontally acquired elements (HAEs) that enhance traits like antibiotic resistance.
- The study highlights the roles of nucleoid-associated proteins (NAPs) like H-NS and TsrA in regulating transcription of HAEs, indicating a complex system of gene expression control necessary for the bacteria's adaptation and virulence.
