N, S, Br co-doped carbon dots: One-step synthesis and fluorescent detection of 6-mercaptopurine in tablet.

Scheme of synthesis of N, S, Br-CDs and fluorescent detection of 6-MP.Image 1.

Synergistic effects boosting hydrogen evolution performance of transition metal oxides at ultralow Ru loading levels.

In this study, ultralow ruthenium nanoparticles on the nickel molybdate nanorods grown on nickel foam (Ru-NiMoO-NF) were synthesized. The Ru-NiMoO-NF exhibited outstanding hydrogen evolution reaction performances in alkaline with overpotential of 52 mV at the current density of 10 mA cm. And, it maintains excellent stability for 20 h at the current density of 20 mA cm.

Carbon Black/Multi-Walled Carbon Nanotube-Based, Highly Sensitive, Flexible Pressure Sensor.

Flexible piezoresistive pressure sensors have promising applications in wearable devices, artificial intelligence, and other fields. However, developing low-cost and high-performance pressure sensors still poses a great challenge. Herein, we utilize low-cost carbon black (CB) and multi-walled carbon nanotubes (MWCNTs) mixed in porous polydimethylsiloxane to assemble a flexible piezoresistive pressure sensor combined with interdigitated electrodes.

Homocouplings of Sodium Arenesulfinates: Selective Access to Symmetric Diaryl Sulfides and Diaryl Disulfides.

Symmetrical diaryl sulfides and diaryl disulfides have been efficiently and selectively constructed via the homocoupling of sodium arenesulfinates. The selectivity of products relied on the different reaction systems: symmetrical diaryl sulfides were predominately obtained under the Pd(OAc) catalysis, whereas symmetrical diaryl sulfides were exclusively yielded in the presence of the reductive Fe/HCl system.

Metal ion-mediated carbon dot nanoprobe for fluorescent turn-on sensing of N-acetyl-l-cysteine.

In this work, carbon dots (CDs) was easily synthesized from aspartic acid through a pyrolysis method. Based on their favourable fluorescence properties, CDs were utilized to design a metal ion-mediated fluorescent probe for N-acetyl-l-cysteine (NAC) detection. The fluorescence intensity of CDs was firstly quenched by manganese ions (Mn ) through static quenching effect and subsequently restored by NAC via the combination with Mn due to the coordination effect.

Multiple fluorescence quenching effects mediated fluorescent sensing of captopril Based on amino Acids-Derivative carbon nanodots.

Carbon nanodots (CNDs) were facilely synthesized through a pyrolysis procedure with histamine, an amino acid rich in element carbon and nitrogen, being the precursor. Taking advantage of the favorable fluorescence performance of CNDs, a multiple fluorescence quenching effects mediated fluorescent sensor was established for captopril (CAP) detection. MnO NPs were firstly combined with CNDs via electrostatic attraction and subsequently quenched the fluorescence.

Synthesis of 4-chalcogenyl pyrazoles via electrophilic chalcogenation/cyclization of α,β-alkynic hydrazones.

A facile method for the synthesis of 4-chalcogenylated pyrazoles has been developed via electrophilic chalcogenation/cyclization of α,β-alkynic hydrazones. The cyclization of α,β-alkynic aldehyde hydrazones could be induced by using either sulfenyl chloride or the S-electrophiles generated in situ from the reaction of NCS and arythiol. The developed method was successfully applied to the synthesis of the sulfenyl analogue of celecoxib.

Blocking Daxx trafficking attenuates neuronal cell death following ischemia/reperfusion in rat hippocampus CA1 region.

Previous studies have shown that the death-associated protein (Daxx) shuttles between nucleus and cytoplasm under ischemic stress, and the subcellular localization of Daxx plays an important role in ischemic neuron death. In this study, by blocking the Daxx trafficking, the rat hippocampus CA1 neurons were protected against cerebral ischemia/reperfusion, and the molecular mechanism underlying this neuroprotection was studied. We found that pretreatment of SP600125, an inhibitor of c-Jun N-terminal kinase (JNK), or an anti-oxidant, N-acetylcysteine (NAC), could not only prevent Daxx from trafficking but also increase the number of the surviving CA1 pyramidal cells of hippocampus at 5days of reperfusion.