Publications by authors named "Yukuai Ma"

Background: Although some studies suggest that sleep deprivation may affect ejaculation regulation, related research is limited, and the mechanisms remain unclear.

Aim: This study aimed to explore whether sleep deprivation influences ejaculation regulation through amyloid-beta and to investigate its potential mechanisms.

Materials And Methods: Normal ejaculating rats were randomly distributed into three separate groups for the study, and treated with sleep deprivation combined with saline gavage, sleep deprivation combined with sodium butyrate gavage, and control with saline gavage.

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Article Synopsis
  • - The study explores how mitochondrial dysfunction could lead to erectile dysfunction (ED) and aims to identify genetic mechanisms and potential drug targets for treatment.
  • - Researchers analyzed various datasets, including gene methylation and expression data, through methods like Mendelian randomization to establish a link between mitochondrial health and ED risk.
  • - Results showed that higher expression of the mitochondrial-related gene FIS1 was associated with a reduced risk of ED, and compounds like resveratrol and quercetin showed promise in targeting this gene for potential ED therapy.
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Background: Since the outbreak of coronavirus disease 2019, it has had a serious impact on people's physical and mental health. However, in our clinical work, we have found that the erectile function of coronavirus disease 2019 patients with neurological decline was often seriously affected.

Objectives: To further explore the relationship between erectile dysfunction and neurological dysfunction caused by coronavirus disease 2019.

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Purpose: Explore the causal relationship between the gut microbiota and erectile dysfunction (ED) at phylum, class, order, family, and genus levels, and identify specific pathogenic bacteria that may be associated with the onset and progression of ED.

Materials And Methods: The genetic variation data of 196 human gut microbiota incorporated in our study came from the human gut microbiome Genome Wide Association Studies (GWAS) dataset released by the MiBioGen Consortium. The GWAS statistics for ED were extracted from one study by Bovijn et al.

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