Publications by authors named "Yuko Tamaoki"
Article Synopsis
- * This study explored the effectiveness of vagus nerve stimulation (VNS) combined with sound exposure to enhance neural responses in the inferior colliculus of VPA-exposed rats.
- * Results showed that VNS paired with multiple tone frequencies improved sound processing by 44%, while VNS paired with a specific speech sound led to a slight decrease in auditory response, suggesting that targeted stimulation can enhance auditory processing in these models.
Background: Individuals with autism spectrum disorders (ASD) often exhibit altered sensory processing and deficits in language development. Prenatal exposure to valproic acid (VPA) increases the risk for ASD and impairs both receptive and expressive language. Like individuals with ASD, rodents prenatally exposed to VPA exhibit degraded auditory cortical processing and abnormal neural activity to sounds.
View Article and Find Full Text PDFBackground: Individuals with autism spectrum disorders (ASD) often exhibit altered sensory processing and deficits in language development. Prenatal exposure to valproic acid (VPA) increases the risk for ASD and impairs both receptive and expressive language. Like individuals with ASD, rodents prenatally exposed to VPA exhibit degraded auditory cortical processing and abnormal neural activity to sounds.
View Article and Find Full Text PDFIntense noise exposure is a leading cause of hearing loss, which results in degraded speech sound discrimination ability, particularly in noisy environments. The development of an animal model of speech discrimination deficits due to noise induced hearing loss (NIHL) would enable testing of potential therapies to improve speech sound processing. Rats can accurately detect and discriminate human speech sounds in the presence of quiet and background noise.
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