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Publications by authors named "Yuko Iwamuro"

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Structure-activity relationship study of novel NR2B-selective antagonists with arylamides to avoid reactive metabolites formation.
Makoto Kawai Isao Sakurada Asato Morita Yuko Iwamuro Kazuo Ando

Bioorg Med Chem Lett

October 2007

A novel potent NMDA-NR2B selective antagonist without the reactive metabolites formation issue was identified. Through this study, a close correlation between reactive metabolites formation and calculated HOMO energies of parent compounds was found.

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