Publications by authors named "Yuko Arakawa"

Article Synopsis
  • - Hypophosphatasia (HPP) is a rare genetic disorder caused by mutations in a specific gene, leading to symptoms like severe musculoskeletal pain, muscle weakness, and early tooth loss.
  • - A case study of a 32-year-old woman with childhood-onset HPP showed significant impairment in daily activities and the need for assistance with housework and child-rearing.
  • - Treatment with the drug asfotase alfa resulted in notable improvements in muscle strength and reduced pain, validated by standardized tests commonly used for other muscular disorders, suggesting these assessments could also be useful for HPP.
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Appropriate management for osteoporosis in adult patients with Prader-Willi syndrome (PWS) has not been established. We report on a 21-year-old woman with PWS, who underwent denosumab treatment for osteoporosis. She presented with fractures and was shown to have very low bone mineral density (BMD), while she had been treated with supplementation of growth hormone for 7-14 years of age and estrogen from 15 years of age.

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This study was designed to evaluate peak inspiratory flow (PIF) and peak expiratory flow (PEF) in 24 patients with mild asthma. After inhalation of a beta2-stimulant (beta2), PIF significantly increased from 173.0 +/- 67.

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