Correlation between hypoxic area in primary brain tumors and WHO grade: differentiation from malignancy using 18F-fluoromisonidazole positron emission tomography.

Background 18F-fluoromisonidazole positron emission tomography (FMISO-PET) has been used for identification of hypoxic areas in tumors, and since hypoxia causes hypoxia-inducible factor-1 and enhancement of tumor growth, identifying the hypoxic area in the tumor tissue is important. Purpose To evaluate the usefulness of FMISO-PET in the grading of primary brain tumors. Material and Methods FMISO-PET was performed preoperatively on 41 consecutive patients with pathologically confirmed brain tumor.

MR Imaging of Uterine Epithelioid Trophoblastic Tumor: A Case Report.

Epithelioid trophoblastic tumor (ETT) is a rare gestational trophoblastic neoplasm of chorionic-type intermediate trophoblasts, and it is most frequently located in the lower uterine segment and endocervix. Due to the epithelial-growth pattern with geographic necrosis exhibited by the neoplastic cells, ETT is commonly confused, both clinically and pathologically, with squamous cell carcinoma. Although there have been no previous reports of ETT focusing on computed tomography (CT) or magnetic resonance imaging (MRI) findings, we report a case of uterine ETT with special attention to the MRI findings referring to the pathological findings and MR images of previous reports.

Detectability and anatomical correlation of middle ear cholesteatoma using fused thin slice non-echo planar imaging diffusion-weighted image and magnetic resonance cisternography (FTS-nEPID).

Cholesteatomas show high intensity in diffusion-weighted imaging (DWI). We performed fused thin slice non-echo planar imaging (EPI) DWI and magnetic resonance cisternography (FTS-nEPID) for cholesteatoma patients to increase the detectability of FTS-nEPID for cholesteatoma. The subjects are 77 consecutive patients who underwent FTS-nEPID as a preoperative study (mean age: 53.

Computed Tomographic Findings of Enterohemorrhagic Escherichia coli O157 Infection: An Analysis of a 7-Case Regional Outbreak.

Purpose: We experienced an outbreak of enterohemorrhagic Escherichia coli (EHEC) colitis. The purpose of this study was to reveal the computed tomographic (CT) findings on EHEC colitis.

Methods: The subjects were 7 patients with EHEC colitis, which was caused by eating a contaminated Japanese rice cake.

Focal deformity of the cranial nerves observed on multislice motion-sensitized driven equilibrium (MSDE) in patients with neurovascular compression.

Objective: Our purpose is to demonstrate the deformity of the cranial nerves by arterial compression using a novel technique, multislice motion-sensitized driven equilibrium (MSDE).

Methods: Subjects were 10 patients with neurovascular compression (5 patients with trigeminal neuralgia and 5 patients with hemifacial spasm). We observed the existence and extent of deformity of nerves by MSDE.

Inverse-direction scanning improves the image quality of whole carotid CT angiography with 64-MDCT.

Purpose: The purpose of this prospective study was to clarify whether reducing the incidence of perivenous artifacts through craniocaudal scanning improves the quality of 64-multidetecter computed tomography (MDCT) angiography images of the whole carotid artery.

Methods: Forty patients underwent MDCT angiography in the caudocranial (n=20) or craniocaudal (n=20) direction in 2007. All patients were injected with 75 ml of contrast media followed by a 35-ml saline chaser bolus at 4.

MR imaging of fetal omphalocele: a case report.

We report a case of a fetal omphalocele in which the internal structure of the hernia sac was imaged in detail by magnetic resonance (MR) imaging. The hernia sac consisted of amnion, Wharton jelly, and externally, peritoneum. The umbilical vascular channels (2 arteries, one vein) were surrounded by Wharton jelly.

Characteristics of three cases of hepatocellular carcinoma showing enhanced technetium-99m-diethylenetriaminepentaacetic acid-galactosyl human serum albumin accumulation by single photon emission computed tomography analysis.

Background: The asialoglycoprotein receptor (ASGP-R) is abundantly expressed on the sinusoidal surfaces of hepatocytes. However, the majority of hepatocellular carcinomas (HCC) lack ASGP-R on their cell surface membranes. We describe three cases of HCC showing increased expression of ASGP-R in comparison with the surrounding liver tissue.

Separate analysis of asialoglycoprotein receptors in the right and left hepatic lobes using (99m)Tc-GSA SPECT in patients with acute hepatic damage.

The asialoglycoprotein receptor (ASGPR) is abundantly expressed on the sinusoidal surfaces of hepatocytes. However, regional expression and clinical significance of the ASGPR in acute hepatic damage is presently unknown. Our aim was to clarify the clinical significance of the regional expression of ASGPR in human livers with acute hepatitis (AH) and fulminant hepatic failure (FHF).

Comparisons of the time-activity curves of the cardiac blood pool and liver uptake by 99mTc-GSA dynamic SPECT and measured 99mTc-GSA blood concentrations.

Objectives: The aim of this study was to determine the time-activity curve in the cardiac and hepatic region by 99mTc-GSA dynamic SPECT which is clinically used in liver scintigraphy and evaluate the temporal changes in the consistency and errors at the absolute scale using the regression equation of changes in the blood concentration of 99mTc-GSA.

Methods: In 11 patients who underwent 99mTc-GSA dynamic SPECT over the 30 min period after IV injection, the percentages of activity in the collected blood and in the blood pool estimated by dynamic SPECT were determined as the plasma clearance by blood collection and as the blood clearance by cardiac pooling. Extrahepatic uptake, expressesd as 100--(% uptake in the liver by dynamic SPECT (%)) was calculated as the blood clearance by the liver.

Morning glory sign: a particular MR finding in progressive supranuclear palsy.

Background And Purpose: We have encountered a peculiar atrophic change in the midbrain in some patients with parkinsonian syndromes. We discovered these patients had vertical supranuclear gaze-palsy, an eye movement disorder. The purpose of this study was to elucidate whether this atrophic pattern of the midbrain (which we have termed morning glory sign) is related to the vertical eye movement disorder, in particular to progressive supranuclear palsy (PSP).

Development of "super rapid dynamic SPECT," and analysis of retention process of 99mTc-ECD in ischemic lesions: comparative study with 133Xe SPECT.

To analyze the retention process of technetium-99m ethyl cysteinate dimer (99mTc-ECD) in normal and ischemic lesions, we developed a super rapid dynamic SPECT system based on the CERASPECT (DSI, Inc., Waltham, MA, USA). The system made it possible to take a SPECT series every 2 seconds.

Separate analysis of asialoglycoprotein receptors in the right and left hepatic lobes using Tc-GSA SPECT.

The asialoglycoprotein receptor (ASGPR) is abundantly expressed on the sinusoidal surfaces of hepatocytes. We aimed to clarify the clinical significance of the regional distribution of ASGPRs in the human liver, especially in chronic viral hepatitis. Eighteen volunteers, 34 patients with chronic hepatitis, and 33 patients with cirrhosis (11/Child-Pugh A, 11/Child-Pugh B, 11/Child-Pugh C) were studied using a newly developed, conventional technetium-99m-diethylenetriaminepentaacetic acid-galactosyl human serum albumin ((99m)Tc-GSA), single photon emission computed tomography (SPECT) method.

Morphology of the inner structure of the hippocampal formation in Alzheimer disease.

Background And Purpose: To our knowledge, inner structural alterations of the hippocampus have never been demonstrated because of the lack of contrast between the hippocampus proper and the superficial medullary lamina. We sought to demonstrate the anatomic details of the inner hippocampus and to elucidate its alterations in Alzheimer disease (AD) in vivo.

Methods: We obtained multishot diffusion- and T2-weighted MR images in 14 healthy control subjects and 26 patients with mild or moderate AD (diagnosis based on Mini-Mental Status Examination scores).

Clinical assessment of hepatic functional reserve using 99mTc DTPA galactosyl human serum albumin SPECT to prognosticate chronic hepatic diseases--validation of the use of SPECT and a new indicator.

Rationale: It is generally known that scintigraphy of 99mTc diethylenetriamine pentaacetic acid-galactosyl human serum albumin (99mTc-GSA) is useful for assessing hepatic functional reserve. For hepatic functional indicators, the index of the calculated planar image has been used in previous studies. However, there have been few reports that suggest that the indicators calculated from static SPECT data would be useful for the assessment of hepatic function.