Publications by authors named "Yukinori Ikeda"
Tumor progression and metastasis are regulated by endothelial cells undergoing endothelial-mesenchymal transition (EndoMT), a cellular differentiation process in which endothelial cells lose their properties and differentiate into mesenchymal cells. The cells undergoing EndoMT differentiate through a spectrum of intermediate phases, suggesting that some cells remain in a partial EndoMT state and exhibit an endothelial/mesenchymal phenotype. However, detailed analysis of partial EndoMT has been hampered by the lack of specific markers.
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- Sprouting angiogenesis is crucial for processes like organ development and healing, with mesenchymal stem cells (MSCs) playing a key role due to their ability to enhance blood vessel formation through interaction with endothelial cells.
- A new 3D in vitro model, microvessel-on-a-chip, was developed to analyze the interactions between human umbilical vein endothelial cells (HUVECs) and MSCs, where MSCs were found to smooth microvessel surfaces and extend angiogenic sprouts.
- Findings revealed that MSCs preferentially positioned themselves around specific areas of the microvessels, contributing to the activation and stabilization of new capillary structures in the engineered tissue model.
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- Cell cultures simplify biological assays and are established for many species, but long-term cultures for marine invertebrates are rare.
- A primary culture system was developed for male and female Japanese scallop cells from gonads, hepatopancreas, and adductor muscle, mimicking natural conditions.
- Attempts at genetic transfection showed promise, with GFP-positive cells detected, potentially aiding in understanding scallop biochemistry and developing immortalized molluscan cell lines.
A total of 39 aroma compounds were detected in the essential oil of Citrus nagato-yuzukichi Tanaka (nagato-yuzukichi) by gas chromatography-mass spectrometry (GC-MS). The essential oil was characterized by a high percentage of monoterpene hydrocarbons (12 components, 90.52%).
View Article and Find Full Text PDFA comparison of volatile components from the peel of Ohshima no. 1 with its parent cultivars.
Biosci Biotechnol Biochem
July 2008
A total of 20 volatile organic compounds from the peel of citrus fruit Ohshima no. 1 were identified by gas chromatography-mass spectrometry (GC-MS). The amount of limonene in Ohshima no.
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