Publications by authors named "Yukino Oura"
Article Synopsis
- A bacterium on human skin creates harmful toxins that can cause skin infections like atopic dermatitis, with these toxins transported in membrane vesicles (MVs) that provoke inflammation in host cells.* -
- A study tested the effects of two polyphenols, EGCG and NOL, finding that EGCG reduced the production of a specific toxin (Staphylococcal Enterotoxin A) and both compounds decreased biofilm formation and virulence-related gene expression.* -
- When the bacterium was grown with these polyphenols, the MVs had lower levels of toxins and led to reduced inflammation in human skin cells, indicating that EGCG and NOL could help manage skin inflammation.*
grows in the skin of patients with atopic dermatitis and the associated symptoms are induced by membrane vesicles (MVs). This study explored the effects of slightly acidic electrolyzed water (SAEW) on the expression of virulence factors of and MV-induced inflammation to uncover the potential of SAEW as a new treatment method for atopic dermatitis. Expression levels of genes related to virulence factors in was assessed and -derived MVs were characterized.
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- - Patients with diabetes have a higher risk of infections, and this study focused on how staphylococcal enterotoxin A (SEA) affects immune cells in diabetic mice.
- - The study examined how two compounds, EGCG and nobiletin, influence inflammation-related gene expression in response to SEA, showing that they work through different mechanisms.
- - Findings suggest that understanding SEA's impact on inflammation in diabetes could help develop strategies using polyphenols to manage these effects.