Publications by authors named "Yukimasa Iwata"
Article Synopsis
- Inguinal hernia and genital edema are common issues for patients undergoing peritoneal dialysis (PD), with patent processus vaginalis (PV) being a potential risk factor that hasn't been fully studied yet.
- A study involving 71 patients found that 22% of those who had laparoscopic catheter placement were diagnosed with patent PV, and only a small number of these patients experienced genital edema post-PD initiation.
- The findings suggest that patent PV might contribute to genital edema, highlighting the need for more research on whether repairing patent PV can prevent this complication in PD patients.
Background: Extra-capillary hypercellularity is a common finding in crescentic glomerulonephritis (GN) and focal segmental glomerulosclerosis (FSGS). In diabetic nephropathy (DN), extra-capillary hypercellularity is often observed as a finding of complications such as IgA nephropathy or microscopic polyangiitis superimposed on DN. However, in rare cases, epithelial cell proliferation may accompany DN.
View Article and Find Full Text PDFSodium-glucose cotransporter 2 inhibitors (SGLT2i) exhibit renoprotective effect in patients with chronic kidney disease (CKD) and reduce serum uric acid (UA) in patients with diabetes mellitus. However, it is not clarified whether SGLT2i reduce serum UA levels in patients with advanced CKD. This study aimed to investigate the impact of SGLT2i on change in serum UA levels in patients with advanced CKD.
View Article and Find Full Text PDFBackground: Management of diabetic kidney disease (DKD) to prevent end-stage kidney disease (ESKD) has become a major challenge for health care professionals. This study aims to investigate the characteristics of patients with DKD when they are first referred to a nephrologist and the subsequent prognoses.
Methods: A total of 307 patients who were referred to our department from October 2010 to September 2014 at Osaka General Medical Center were analyzed.
Background: The diagnosis of diabetic nephropathy (DN), the major cause of ESKD, requires kidney biopsy. d-Serine, present only in trace amounts in humans, is a biomarker for kidney diseases and shows potential to distinguish the origin of kidney diseases, whose diagnoses usually require kidney biopsy. We extended this concept and examined the potential of d-serine in the diagnosis of DN.
View Article and Find Full Text PDFArticle Synopsis
- D-Serine is identified as a potential biomarker for chronic kidney disease (CKD), which varies in its underlying causes and typically requires kidney biopsies for diagnosis.
- The study measured D- and L-serine levels in patients with different kidney diseases, using advanced chromatography techniques to analyze the relationships between D-serine levels and the origins of these diseases.
- Results indicated that D-serine levels are significant in detecting kidney diseases, with specific plasma and urinary patterns helping to differentiate the causes, especially in cases of lupus nephritis.
Background: Idiopathic membranous nephropathy (MN) is one of the major glomerulonephritis that cause nephrotic syndrome. The phospholipase A receptor (PLAR) has recently been identified as an endogenous antigen of idiopathic MN. Thrombotic thrombocytopenic purpura (TTP) is a disorder characterized by schistocytes, hemolytic anemia, thrombocytopenia, and organ dysfunction which occurs as a result of thrombi.
View Article and Find Full Text PDFBackground: The duration of predialysis nephrological care that can reduce all-cause and cardiovascular mortality after dialysis initiation has not been clarified.
Methods: A total of 1117 patients who started chronic dialysis treatment from 2006 to 2015 at Osaka General Medical Center were analyzed. Independent risk factors associated with all-cause and cardiovascular mortality after dialysis initiation and early death (death within 12 months after dialysis initiation) were identified using Cox proportional hazards analysis.