Publications by authors named "Yukiko Toda"
Human induced pluripotent stem cells (hiPSCs) are a promising cell source for elucidating disease pathology and therapy. The mass supply of hiPSC-derived cells is technically feasible. Carriers that can contain a large number of hiPSC-derived cells and evaluate their functions in vivo-like environments will become increasingly important for understanding disease pathogenesis or treating end-stage organ failure.
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- Fractional flow reserve (FFR) is a technique used to evaluate how significant coronary artery blockages are, typically using adenosine triphosphate (ATP) to gauge blood flow.* -
- This study assessed the use of nicorandil, a drug that dilates blood vessels, as an alternative to ATP for FFR measurements in patients with coronary artery disease.* -
- Findings showed that nicorandil and ATP produced strongly correlated FFR results, but nicorandil had fewer adverse effects and caused less drop in blood pressure, suggesting it may be a safer option for FFR testing.*