Publications by authors named "Yukiko Takarabe"
KSP-1007 is a novel bicyclic boronate-based broad-spectrum β-lactamase inhibitor and is being developed in combination with meropenem (MEM) for the treatment of infections caused by carbapenem-resistant Gram-negative bacteria, a global health concern, and here, we describe its characteristics. KSP-1007 exhibited low apparent inhibition constant ( ) values against all classes of β-lactamase, including imipenemase types and oxacillinase types from . Against 207 and 55 .
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- Hand hygiene is essential for controlling COVID-19, but the extent of SARS-CoV-2 contamination on the hands of healthy individuals was unclear, prompting this study aimed at evaluating contamination levels.
- Researchers collected swab samples from 925 healthy participants, including various professionals and students, and analyzed them for viral RNA using RT-qPCR.
- The findings revealed that SARS-CoV-2 RNA was detected in only 0.32% of samples, with no viable viruses found, indicating that the risk of transmission through hand contact in everyday settings is very low.
Article Synopsis
- Researchers studied the presence of SARS-CoV-2 in the homes of COVID-19 patients to understand how the virus spreads within families.
- They collected samples from various surfaces over a week, conducting tests to identify both viral RNA and viable viruses.
- While they found traces of SARS-CoV-2 RNA on surfaces like pillows and doorknobs, no live viruses were detected, indicating a low risk of transmission from contaminated surfaces.
Article Synopsis
- The study aimed to determine the presence of viable SARS-CoV-2 versus just its RNA in hospital environments to improve infection control for COVID-19.* -
- Researchers collected samples from various surfaces and patient saliva over the course of treatment, finding that while viral RNA was common, viable virus was rare and mostly found in sinks.* -
- The findings indicate that the risk of contracting COVID-19 from surfaces in hospital rooms is very low, as viable virus was only detected in a small fraction of samples.*
Background: Although crowds are considered to be a risk factor for SARS-CoV-2 transmission, little is known about the changes in environmental surface contamination with the virus when a large number of people attend an event. In this study, we evaluated the changes in environmental surface contamination with SARS-CoV-2.
Methods: Environmental samples were collected from concert halls and banquet rooms before and after events in February to April 2022 when the 7-day moving average of new COVID-19 cases in Tokyo was reported to be 5000-18000 cases per day.