Publications by authors named "Yukiko Itaya"

Aim: To investigate the efficacy and safety of long-term adjusted low-dose gonadotropin-releasing hormone agonist therapy (GnRH agonist drawback therapy) with nafarelin acetate in patients with uterine fibroids and/or adenomyosis with menstrual symptoms.

Methods: This single-center, retrospective, observational study initially included 118 patients with uterine fibroids and/or adenomyosis with menstrual symptoms who had received GnRH agonist (nafarelin acetate) drawback therapy for at least 7 months between 2010 and 2020. Blood hemoglobin level, maximum fibroid diameter, area of the corpus uteri, blood estradiol level, daily dosage of nafarelin acetate, and bone density in the lumbar spine and femoral neck were assessed before and after the treatment initiation.

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Background: Most cases of traumatic injury during pregnancy involve blunt trauma, with penetrating trauma being uncommonly rare. In glass shard injuries, fragments often penetrate deeply, and multiple injuries may occur simultaneously; attention must be paid to the possibility of organ injury from the residual fragments. However, no case of this occurring during pregnancy has been reported yet.

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Background: Progestin-primed ovarian stimulation (PPOS) has been used in infertility cases in recent years, and several reports have stated that it has oocyte collection results similar to those of gonadotropin-releasing hormone antagonist (GnRH-ant) protocol. For emergency fertility preservation, random-start ovarian stimulation is usually recommended. Therefore we compared the clinical outcomes of random-start PPOS with those of conventional random-start GnRH-ant protocols in fertility-preserving cases.

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Article Synopsis
  • * A 29-year-old woman experienced abdominal hemorrhage after resuming letrozole just two days post-oocyte retrieval, leading to severe pain and a necessary surgical intervention.
  • * It's important for reproductive-medicine practitioners to recognize that restarting letrozole after oocyte retrieval can cause complications, such as ovarian stimulation and hemorrhage, and to take precautions.
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Objectives: Pregnancy complicated with ovarian endometrioma is a risk factor for preterm delivery and rupture or infection during pregnancy. This study aimed to clarify the effectiveness and safety of transvaginal aspiration during pregnancy for endometrioma diagnosed in the first trimester.

Design: This retrospective observational study included 8 pregnant women with endometrioma who underwent transvaginal cyst aspiration at 12-14 weeks (aspiration group) between March 2011-March 2018 and 23 pregnant women with endometrioma who refused aspiration during the same period (observation group).

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Background: Ovarian hyperstimulation syndrome is normally induced by ovarian stimulation drugs. Severe cases of ovarian hyperstimulation syndrome involve complications such as renal failure and thrombosis. Evidence has recently been developed for a method to prevent ovarian hyperstimulation syndrome.

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  • Edwardsiella tarda (E. tarda) is a rare bacteria that can cause serious infections in humans, particularly during the peripartum period (around childbirth).
  • A case study highlighted a mother who developed severe health issues, including septicemia, after experiencing chorioamnionitis, leading to complications like septic shock and an abscess after a cesarean section.
  • The mother recovered following a combination of treatments, while E. tarda was found in her blood and various samples from her newborn, underscoring the dangerous potential of this infection for both mother and child.
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  • This study looks at how postpartum recovery differs in women with pre-eclampsia (PE) and gestational hypertension (GH), focusing on factors that influence recovery.
  • Researchers reviewed data from 145 patients who gave birth between 2008 and 2011, noting aspects like blood pressure normalization and proteinuria resolution times.
  • Results showed that blood pressure took about 41.8 days to normalize and proteinuria around 30 days, with early-onset pregnancies resulting in longer recovery times, while proteinuria severity impacted recovery more than GH severity.
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