Publications by authors named "Yukihito Nakano"
Article Synopsis
- The study investigated how oxidative stress and thromboxane A (TXA) contribute to kidney damage in hypertension using a specific rat model (SHRSP).
- It was found that SHRSP exhibited significantly higher levels of thromboxane synthase (TXAS) mRNA in their kidneys compared to normal rats, alongside increased heme oxygenase-1 mRNA.
- Surprisingly, treating SHRSP with tempol (an antioxidant) worsened kidney damage, while using ozagrel (a TXAS inhibitor) improved it, suggesting that targeting TXA may be more effective than focusing on oxidative stress for treating kidney injuries in hypertension.
Cryoglobulinemia can induce systemic vasculitis affecting various organs such as skin, peripheral nerves, and kidney. The disease can induce chronic organ failure and even be life-threatening. Cryofiltration has been applied for the treatment of cryoglobulinemic vasculitis.
View Article and Find Full Text PDFAn 81-year-old man presented with sudden-onset paraplegia. Cerebrospinal fluid examination revealed an increased cell count and an elevated protein level; the patient also tested positive for the oligoclonal band (OCB). Gadolinium-enhanced MRI revealed a thoracic cord lesion.
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