Male patients with adult spinal deformity: sex differences in demographics, radiography, and complications.

Purpose: This study aimed to investigate sex-related differences in demographics, radiography, and perioperative complications in adult spinal deformity (ASD) surgeries.

Methods: This retrospective cohort, single-center study enrolled patients who underwent long-instrumented fusion from the thoracic spine to the ilium for ASD, with a minimum follow-up of 2 years. The incidence of preoperative comorbidities, perioperative complications, and postoperative mechanical complications was analyzed.

Residual T1 tilt could lead to poor self-image for patients with Lenke type 1 adolescent idiopathic scoliosis.

Study Design: Retrospective study.

Purpose: We aimed to investigate the clinical impact and risk factors for residual T1 tilt in patients with adolescent idiopathic scoliosis (AIS).

Methods: We retrospectively analyzed data of patients with AIS and Lenke type 1 curves who underwent posterior fusion.

Zones where reduced implant density leads to correction loss after scoliosis surgery for Lenke 1A adolescent idiopathic scoliosis: a multicenter study.

Purpose: Investigate zones where implant density should not be reduced in posterior spinal fusion (PSF) for adolescent idiopathic scoliosis (AIS) Lenke type 1A curves.

Methods: 126 consecutive patients (118 female and 8 male; mean age: 15.1 ± 2.

Difficulty in bone union after arthrodesis to treat Charcot arthropathy of the foot and ankle.

Introduction: A major complication of arthrodesis is non-union in patients with Charcot arthropathy. This study examined the bone union in joints affected arthrodesis for Charcot arthropathy of the foot and ankle.

Methods: The current retrospective study enrolled 15 patients (20 feet) who underwent arthrodesis (performed in 47 joints) for Charcot arthropathy from 2014 to 2020.

Efficacy of Chemonucleolysis with Condoliase in Patients Aged under 20 Years.

Introduction: Chemonucleolysis with condoliase is a minimally invasive treatment option for lumbar disk herniation (LDH). However, studies reporting the efficacy of condoliase in patients aged <20 years are scarce. Therefore, the present study aimed to evaluate the efficacy of condoliase therapy for LDH in the aforementioned population.

A phase 3, randomized, double-blind, sham-controlled trial of SI-6603 (condoliase) in patients with radicular leg pain associated with lumbar disc herniation.

Background Context: SI-6603 (condoliase) is a chemonucleolytic agent approved in Japan in 2018 for the treatment of lumbar disc herniation (LDH) associated with radicular leg pain. Condoliase, a mucopolysaccharidase with high substrate specificity for glycosaminoglycans (GAGs), offers a unique mechanism of action through the degradation of GAGs in the nucleus pulposus. As LDH management is currently limited to conservative approaches and surgical intervention, condoliase could offer a less invasive treatment option than surgery for patients with LDH.

Adjacent segment degeneration at a minimum 2-year follow-up after posterior lumbar interbody fusion: the impact of sagittal spinal proportion: a retrospective case series.

Study Design: A retrospective cohort study.

Purpose: To investigate the sagittal plane configuration of the entire spine and its association with the risk of adjacent segment degeneration (ASD) after posterior lumbar interbody fusion (PLIF).

Overview Of Literature: Although PLIF has demonstrated satisfactory clinical outcomes, it is associated with ASD.

Excessive posterior placement of upper instrumented vertebra relative to lower instrumented vertebra as a predictor of proximal junction kyphosis after selective spinal fusion for adolescent idiopathic scoliosis Lenke type 5C curves.

Purpose: We defined sagittal S-line tilt (SSLT) as the tilt of the line connecting the upper instrumented vertebra and the lower instrumented vertebra. This study aimed to: (1) examine the correlation between SSLT and proximal junctional angle (PJA) change values, and (2) determine the cut-off value of SSLT with respect to proximal junctional kyphosis (PJK) occurrence.

Methods: Eighty-six consecutive patients (81 female and 5 male; mean age: 15.

Impact of implant positions in total knee arthroplasty on the postoperative knee kinematics of tibial rotation.

Introduction: In total knee arthroplasty (TKA), the implant positions and knee kinematics, as well as the manifestation of medial pivot motion, play pivotal roles in determining postoperative clinical outcomes. The purpose of the current study was to analyze the correlation between knee kinematics, which was measured during TKA and implant positions derived using computed tomography (CT) examination after TKA.

Methods: This study comprised 64 patients (76 knees) who underwent primary TKA between 2015 and 2022.

Implications of the diagnosis of locomotive syndrome stage 3 for long-term care.

Objectives: Locomotive syndrome stage 3 (LS3), which has been established recently, may imply a greater need for care than LS stage 0 (LS0), LS stage 1 (LS1), and LS stage 2 (LS2). The relationship between LS3 and long-term care in Japan is unclear. Therefore, this study aimed to examine this relationship.

Relationship between the perioperative prognostic nutritional index and postoperative gait function in elderly hip fractures.

Objectives: We investigated the relationship between the perioperative nutritional status and postoperative walking ability in patients with hip fractures.

Methods: We included 246 surgically treated elderly patients with hip fractures who were ambulatory before the injury. Patients were divided into two groups: group A, who were able to walk at discharge, and group B, who were unable to walk at discharge.

Enhancing the Unicompartmental Knee Arthroplasty Safety via Finite Element Analysis of Coronary Plane Alignment: A Case Report.

Although Oxford unicompartmental knee arthroplasty is often used to successfully treat patients with knee osteoarthritis isolated at the medial compartment, we present a case of fracture just below the tibial keel caused by either a shift in medial loading position or an increased amount of tibial osteotomy. Finite element analysis was used to determine which factor was more important. First, a 3D-surface model of the patient's tibia and the implant shape were created using computed tomography-Digital Imaging and Communications in Medicine (CT-DICOM) data taken preoperatively.

Wound Closure and Wound Dressings in Adult Spinal Deformity Surgery From the AO Spine Surveillance of Post-Operative Management.

Study Design: An e-mail-based online survey for adult spinal deformity (ASD) surgeons.

Objective: Wound closure and dressing techniques may vary according to the discretion of the surgeon as well as geographical location. However, there are no reports on most common methods.

Opioid Use Prior to Adult Spine Deformity Correction Surgery is Associated With Worse Pre- and Postoperative Back Pain and Prolonged Opioid Demands.

Study Design: Prospective multicenter database post-hoc analysis.

Objectives: Opioids are frequently prescribed for painful spinal conditions to provide pain relief and to allow for functional improvement, both before and after spine surgery. Amidst a current opioid epidemic, it is important for providers to understand the impact of opioid use and its relationship with patient-reported outcomes.

Background factors for intra-operative hypotension during hip fracture repair surgery in the elderly under spinal anesthesia managed by orthopedic surgeons: A retrospective case-control study.

Background: Spinal anesthesia is used for femoral trochanteric fracture surgery, but frequently induces hypotension and the causative factors remain unclear. We examined background factors for the use of an intraoperative vasopressor in elderly patients receiving spinal anesthesia for femoral trochanteric fracture surgery.

Methods: We retrospectively analyzed 203 patients >75 years (mean age, 87.

Psychological Factors Can Affect the Clinical Outcome of Chemonucleolysis with Condoliase in Patients with Lumbar Disk Herniation.

Introduction: Condoliase-based chemonucleolysis is a minimally invasive intermediate treatment option between conservative approaches and surgical interventions for lumbar disk herniation (LDH). In this study, the effects of psychological factors on the clinical outcomes of condoliase therapy for LDH were assessed.

Methods: This study involved patients with LDH who received condoliase injections over a 1-year follow-up period.

Impact of the sagittal spinopelvic and coronal lower extremity alignments on clinical outcomes after medial unicompartmental knee arthroplasty.

Introduction: We evaluated whether the clinical outcomes, including postoperative knee range of motion (ROM), after unicompartmental knee arthroplasty (UKA) were associated with the sagittal spinopelvic parameters and coronal alignment of the full lower extremity.

Methods: Forty-two patients (50 knees: six men, seven knees; 36 women, 43 knees) who underwent medial UKA between April 2015 and December 2022 were included. Preoperative radiographic examinations of the index for sagittal spinopelvic alignment included the sagittal vertical axis (SVA), lumbar lordosis, sacral slope (SS), pelvic tilt (PT), and pelvic incidence.