Rubella Virus Genotype 1E in Travelers Returning to Japan from Indonesia, 2017.

Although rubella is epidemic in Indonesia, the phylogenetic profile of circulating rubella virus strains has not been clarified. In 2017, rubella virus was detected in 2 travelers who returned from Indonesia to Japan. These strains were classified into genotype 1E lineage 2, which may be an indigenous strain in Indonesia.

Synthesis, structural analysis of the hetero-bimetallic complexes MMe[(O-2,4-tBu2C6H2-6-CH2)2(μ2-O-2,4-tBu2C6H2-6-CH2)N][Me2Al(μ2-OiPr)] [M = Zr, Hf] and their use in catalysis for ethylene polymerisation.

The synthesis and structural analysis of the hetero-bimetallic M-Al complexes MMe[(O-2,4-(t)Bu2C6H2-6-CH2)2(μ2-O-2,4-(t)Bu2C6H2-6-CH2)N][Me2Al(μ2-O(i)Pr)] [M = Zr, Hf], prepared from M(O(i)Pr)[{(O-2,4-(t)Bu2C6H2)-6-CH2}3N] by treating with 1.0 equiv. of AlMe3, have been explored: these complexes exhibited catalytic activities for ethylene polymerisation in n-octane in the presence of methylaluminoxane (MAO).

Ultrasensitive DNA chip: gene expression profile analysis without RNA amplification.

We have developed a new DNA chip whose substrate has a unique minute columnar array structure made of plastic. The DNA chip exhibits ultrahigh sensitivity, up to 100-fold higher than that of reference DNA chips, which makes it possible to monitor gene expression profiles even with very small amounts of RNA (0.1-0.

Scanning electrochemical microscopy-based drug sensitivity test for a cell culture integrated in silicon microstructures.

The respiratory activity of collagen-embedded living cells was imaged by scanning electrochemical microscopy (SECM) with the objective to study anticancer drug sensitivity. Two kinds of cancer cells, the human erythroleukemia cell line (K562) and its adriamycin-resistant subline (K562/ADM), were immobilized at the array of microholes micromachined on a silicon wafer for comparative characterization of their sensitivity to the anticancer drug, ADM. The results obtained by the SECM method showed correspondence to a conventional colorimetric assay (SDI assay).