Publications by authors named "Yuki Shina"
Background: Multiple deep organ abscesses associated with Staphylococcus aureus bloodstream infection (SAB) have a high mortality rate, requiring rapid removal or drainage of infective foci with long-term appropriate antimicrobial therapy. Cases in which infective foci cannot be completely removed are challenging for their management.
Case Presentation: A 77-year-old man developed multiple deep organ abscesses associated with SAB.
Article Synopsis
- Chronic lung allograft dysfunction (CLAD) significantly affects long-term survival post-lung transplantation and involves both allogeneic immunity and autoimmunity.
- A rat orthotopic lung transplantation model was created in the 1970s, but limitations in available transgenic and knockout strains hinder further CLAD research.
- New findings indicate that minor histocompatibility antigen mismatches lead to CLAD in murine orthotopic lung transplants, highlighting the dependence on interleukin-17, and the review discusses the evolution and future potential of rodent models for studying CLAD.