Publications by authors named "Yuki Iida"
Background: The significance of lymph node dissection (LND) in primary debulking surgery (PDS) for advanced ovarian cancer was demonstrated in the LION trial. However, the role and the current practices of LND during interval debulking surgery (IDS) remains unclear. We aimed to conduct a survey of the current LND practices.
View Article and Find Full Text PDFIntroduction: The Hugo robotic-assisted surgery (RAS) system is a novel surgical platform that expands the potential for minimally invasive procedures in gynecologic oncology. Early studies have shown promise, but the optimal configuration of ports and robotic arms requires further clarification. This study aimed to introduce a refined strategy for optimizing port placement and robotic arm arrangement with the Hugo RAS system and compare its performance to previously employed configurations.
View Article and Find Full Text PDFBackground: This study evaluated the effectiveness of preoperative inflammatory response markers in distinguishing clear cell carcinoma (CCC) and endometrioid carcinoma (EC) from ovarian endometrioma.
Methods: Patients with stage I ovarian cancer with histology CCC/EC or endometrioma who underwent surgery at our institution between 2010 and 2021 were included. Preoperative inflammatory response markers evaluated were white blood cell count, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), fibrinogen, D-dimer, neutrophil/lymphocyte ratio (NLR), platelet count/lymphocyte ratio (PLR), and systemic immune-inflammation index (SII).
Background: Pose estimation algorithms applied to two-dimensional videos evaluate gait disturbances; however, a few studies have used this method to evaluate ataxic gait.
Objective: The aim was to assess whether a pose estimation algorithm can predict the severity of cerebellar ataxia by applying it to gait videos.
Methods: We video-recorded 66 patients with degenerative cerebellar diseases performing the timed up-and-go test.
Aim: In the PEMA-FL study in patients with metabolic dysfunction-associated steatotic liver disease (MASLD), pemafibrate was shown to significantly decrease low-density lipoprotein cholesterol (LDL-C) levels. We aimed to investigate the mechanisms of pemafibrate-induced LDL-C reduction in patients with MASLD by conducting an additional sub-analysis of the PEMA-FL study.
Methods: The PEMA-FL study randomized 118 patients with MASLD to receive pemafibrate or placebo for 72 weeks.
Article Synopsis
- This study evaluated the practical application of cardiovascular physical therapy for older heart failure patients in Japan, utilizing data from a national registry of hospitalized patients aged 65 and older.
- The assessment showed a high completion rate for evaluations, with over 80% successfully completing physical therapy; however, gait speed and short-performance tests had lower completion rates for those with lower Barthel Index scores.
- The findings suggest that while routine assessments of medical conditions are feasible in hospitals, interventions focused on gait and muscle strength training are more prevalent than aerobic or resistance exercise among these patients.
Recently, a Letter to the Editor critiquing the recommendations of the Japanese Clinical Practice Guidelines for Rehabilitation in Critically Ill Patients, 2023, was published. The comment centered on the recommendation, "Weak recommendation against the use of endoscopy-based management (GRADE 2D: certainty of evidence = 'very low')" for the clinical question, "Should critically ill patients be managed based on video endoscopic assessment of swallowing?" In response, we outline the rationale behind our recommendations and their clinical implications.
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- The study investigates the use of pose estimation algorithms to distinguish between Parkinson's disease (PD) and spinocerebellar degeneration (SCD) through video analysis of patient gait.
- Researchers recorded 82 PD patients and 61 SCD patients during a mobility test and utilized a deep neural network model trained on gait data to make predictions on the neurological disorder.
- Results indicated high accuracy (0.86), sensitivity (0.94), and specificity (0.75) for differentiating PD from SCD, suggesting this method could be valuable in clinical settings and telemedicine for improved patient assessment.
Background: The da Vinci surgical systems (X and Xi) are fourth-generation systems marketed by Intuitive Inc. The X system is less expensive than the Xi system. This study compared the surgical outcomes of patients who underwent hysterectomy using the X and Xi systems.
View Article and Find Full Text PDFIntroduction: Hybrid total laparoscopic hysterectomy combines conventional laparoscopic surgery and robot-assisted devices: the camera and assistant forceps are operated by a robotic device, whereas the surgeon performs laparoscopic procedures, enabling surgery with a completely fixed field of view and significantly reducing errors in forceps grasping and needle misalignment. Here, we examined whether using two arms of the Hugo™ robot-assisted surgery system, one for the camera and one for the assistant, would improve surgical accuracy compared with conventional total laparoscopic hysterectomy.
Materials And Surgical Technique: The surgical system reduced surgeon errors in grasping the forceps during training and stabilized forceps operation.
Background: Amphoterin-induced gene and open reading frame 2 (AMIGO2) have been reported to be related to the prognosis of colorectal, gastric, and cervical cancer. However, their association with ovarian cancer remains unclear. This study aimed to elucidate the role of AMIGO2 in ovarian cancer.
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- Dysphagia, or difficulty swallowing, is common in critically ill patients, and various rehabilitation methods are used globally to treat it.
- A review of randomized controlled trials found that dysphagia rehabilitation reduced the risk of pneumonia but did not significantly affect mortality or health-related quality of life.
- The analysis included 19 trials with over 1,000 participants, indicating moderate certainty that rehabilitation helps with pneumonia but very low certainty concerning its effects on mortality and quality of life.
Background: Lung resection is the standard of care for patients with clinical stage I/II non-small cell lung cancer. This surgery reduces both the duration and quality of patients' daily ambulatory activities 1 month after surgery. However, little is known about physical activity after lung resection in patients with lung cancer.
View Article and Find Full Text PDFFew studies have compared the efficacy of robot-assisted, laparoscopic, and open surgeries for endometrial cancer. When considering the position of robotic surgery in Japan, it was necessary to determine whether it was effective or not. We aimed to compare the efficacy and safety of these three types of surgeries for early-stage endometrial cancer.
View Article and Find Full Text PDFBackground And Objective: Interstitial lung disease (ILD) is characterized by dyspnoea on exertion and exercise-induced hypoxaemia. High-flow nasal cannula (HFNC) therapy reduces the respiratory workload through higher gas flow and oxygen supplementation, which may affect exercise tolerance. This study aimed to examine the effects of oxygen and gas flow rates through HFNC therapy on exercise tolerance in ILD patients.
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- Post-intensive care syndrome (PICS) involves physical, mental, and cognitive impairments in ICU patients that can persist long after their hospital stay and also affects their families.* -
- Recent research has expanded knowledge about PICS, focusing on its causes, prevalence, assessment methods, risk factors, and potential prevention and treatment strategies.* -
- Continued research is essential to understand the underlying mechanisms of PICS and to develop effective therapies and interventions for those affected.*
Psychological aspects of rehabilitation nutrition affect physical, cognitive, and social rehabilitation nutrition. When depression is recognized, not only pharmacotherapy and psychotherapy, but also non-pharmacological therapies such as exercise, nutrition, psychosocial, and other interventions can be expected to improve depression. Therefore, accurate diagnosis and intervention without overlooking depression is important.
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- A study analyzed the incidence of hospitalization-associated disability (HAD) in older heart failure patients in Japan, finding that 37.1% of the 9,403 participants experienced HAD during their hospital stay.
- Patients with HAD were generally older and had higher rates of comorbidities such as hypertension and chronic kidney disease, along with lower functional scores prior to admission.
- The research suggests that factors like age and prehospital health status are linked to the development of HAD, highlighting the need for increased rehabilitation efforts for older heart failure patients in Japan.
Malignant pericardial effusion is an uncommon metastatic manifestation of ovarian carcinoma. Few cases of ovarian serous carcinoma have been previously reported. Ovarian clear cell carcinoma is the second most common histologic subtype in East Asian countries and is a relatively rare in Western countries.
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- This study investigates the use of deep neural networks (DNNs) to differentiate between speech patterns of patients with Parkinson's disease (PD) and spinocerebellar degeneration (SCD) using their speech data.
- It utilized speech recordings from 251 PD patients and 101 SCD patients to fine-tune a pre-trained DNN model that analyzed log-mel spectrograms to classify the speech data.
- The model demonstrated strong performance with an average AUC of 0.93, indicating it is an effective non-invasive tool for distinguishing between these neurodegenerative diseases, potentially useful in telemedicine applications.
Article Synopsis
- The study aimed to address the challenges of assessing post-intensive care syndrome (PICS) in ICU survivors by identifying effective assessment instruments through a scoping review and consensus process.
- A total of 6972 records were reviewed, leading to 20 recommended instruments spanning various domains, including physical health, cognition, and mental health.
- The findings provide a structured approach to evaluating PICS, highlighting tools like the 6-min walk test and MoCA, ensuring comprehensive assessment for ICU survivors and their families.
Providing standardized, high-quality rehabilitation for critically ill patients is a crucial issue. In 2017, the Japanese Society of Intensive Care Medicine (JSICM) promulgated the "Evidence-Based Expert Consensus for Early Rehabilitation in the Intensive Care Unit" to advocate for the early initiation of rehabilitations in Japanese intensive care settings. Building upon this seminal work, JSICM has recently conducted a rigorous systematic review utilizing the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methodology.
View Article and Find Full Text PDFAims: Malnutrition is prevalent among patients with heart failure (HF); however, the effects of coexisting malnutrition and frailty on prognosis are unknown. This study examines the impact of malnutrition and frailty on the prognosis of patients with HF.
Methods And Results: We examined 1617 patients with HF aged 65 years or older (age: 78.
Objective: During the mastication of solid food, the tongue pushes the bolus laterally to place it onto occlusal surfaces as the jaw is opened. This movement is referred to as tongue-pushing (TP). TP has an important role in efficient chewing, but its kinematic mechanisms remain unclear.
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- This study compared robotic-assisted hysterectomy (RAH) and total laparoscopic hysterectomy (TLH) for treating benign gynecological diseases at Tottori University Hospital from January 2018 to May 2022.
- It included 40 patients in the RAH group and 44 in the TLH group, evaluating metrics like total operative time and learning curve.
- The results showed that after about 30 RAH surgeries, the total operative time was similar to TLH, and after about 10 surgeries, the operative time for RAH was also comparable to TLH.