Publications by authors named "Yuki Hara"

Carpal tunnel syndrome (CTS) and cervical spondylosis (CS) are both common diseases, yet differentiation between the two is sometimes necessary. However, there are few evidence-based reviews on the differentiation of these conditions. This review examined the literature on the diagnosis of CTS and CS, focusing on how to distinguish between them.

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Gangrenous cholecystitis (GC) is classified as moderate acute cholecystitis according to the Tokyo Guidelines from 2018 (TG18). We evaluated the risk factors for GC and the outcomes of early cholecystectomy. A total of 136 patients who underwent emergency cholecystectomy for acute cholecystitis were retrospectively analyzed; 58 of these patients (42.

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Background: During hearing aid (HA) fitting, individuals may experience better speech discrimination at normal speech levels and worse discrimination at loud speech levels than without an HA. Therefore, we investigated factors that worsen speech discrimination when the speech sound level increases.

Methods: Speech discrimination was measured in patients aged >20 years who had average hearing thresholds <90 dB on pure-tone audiometry.

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Background: Spontaneous anterior interosseous nerve (AIN) palsy is characterized by the sudden onset of upper limb pain followed by weakness of muscles mainly innervated by the AIN. Although this palsy is conventionally treated conservatively, interfascicular neurolysis to release hourglass-like fascicular constrictions has been recommended. The present study aimed to establish the clinical characteristics and treatment strategy for this condition.

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In patients with anterior shoulder instability (ASI), a chronic imbalance might exist between the anterior and posterior shoulder muscles (i.e., subscapular [Ssc] vs.

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Introduction: Aromatase inhibitors (AIs) are the standard treatment for early breast cancer (EBC) and are typical causative agents of cancer treatment-induced bone loss. However, the effects of long-term treatment with these drugs on bone microstructure remain unclear.

Materials And Methods: This prospective, single-arm observational study included postmenopausal, non-osteoporotic women with hormone receptor-positive EBC.

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Phyllodes tumors (PT) are fibroepithelial neoplasms that are treated by complete surgical excision. The effectiveness of adjuvant therapies, including radiotherapy and chemotherapy, for PT remains unclear, and the use of neoadjuvant chemotherapy (NAC) is yet to be established. We report a case of a 15-year-old girl with acute lymphatic leukemia (ALL) who was incidentally diagnosed with a 50-mm borderline PT in the left breast using computed tomography, ultrasonography, and histological examination following needle biopsy.

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Article Synopsis
  • Hypertensive emergencies can lead to serious organ damage, and this study aimed to investigate the role of the renin-angiotensin-aldosterone system (RAS) in such cases.
  • The study included 63 patients with severe hypertension and various organ injuries, assessing their blood pressure and aldosterone levels.
  • Results showed that higher aldosterone levels were linked to more organ damage and complications, suggesting that RAS plays a significant role in affecting patient outcomes during hypertensive emergencies.
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Introduction: Chemotherapy involves the administration of steroids to prevent nausea and vomiting; however, its effect on bone microstructure remains unknown. This study aimed to evaluate the changes in bone mineral density (BMD) and bone microstructure associated with chemotherapy using high-resolution peripheral quantitative computed tomography (HR-pQCT) in women with early breast cancer.

Materials And Methods: This prospective single-arm observational study included non-osteoporotic, postmenopausal women with breast cancer.

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  • * It involved 321 patients divided into three groups based on their kidney function, utilizing data from both kidneys and different MRI methods.
  • * The model achieved its highest accuracy of 86.2% when analyzing images from both kidneys using the in-phase technique, indicating its effectiveness in assessing CKD severity.
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Purpose: This study assessed the serial volume changes in multiple shoulder muscles simultaneously following arthroscopic rotator cuff repair (ARCR) by a three-dimensional (3D) modeling-based sectional measurement. These volume changes were correlated with background preoperative factors.

Methods: Four consecutive magnetic resonance imaging scans (preoperatively and postoperatively at 3, 6, and 12 months) of 33 shoulders from 31 patients who underwent arthroscopic rotator cuff repair were examined.

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This study performed three-dimensional (3D) magnetic resonance imaging (MRI)-based statistical shape analysis (SSA) by comparing patellofemoral instability (PFI) and normal femur models, and developed a machine learning (ML)-based prediction model. Twenty (19 patients) and 31 MRI scans (30 patients) of femurs with PFI and normal femurs, respectively, were used. Bone and cartilage segmentation of the distal femurs was performed and subsequently converted into 3D reconstructed models.

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Background: The recently developed anti-human epidermal growth factor receptor 2 (HER2) therapy has substantially improved the prognosis of HER2-positive breast cancer. The DESTINY-Breast04 trial results showed that trastuzumab deruxtecan (T-DXd) significantly prolonged the survival of patients with HER2-low breast cancer, thus presenting a paradigm shift in anti-HER2 therapy. This may facilitate a change in the treatment strategy for HER2-low breast cancer.

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  • Myoelectric hands help individuals with upper-limb deficiencies but are ineffective for those with short stumps or paralysis, prompting the development of a new electric prosthetic hand using wireless sensor technology.
  • A study compared this new prosthetic hand with a standard myoelectric hand (Ottobock), involving ten healthy therapists who tested both devices on fixed forearms while performing specific tasks.
  • Although no significant performance differences were found, the new prosthetic hand showed a smaller increase in fatigue (measured by the Borg scale), indicating its potential for broader use among people with upper-limb deficiencies.
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Purpose: We compared cerebrospinal fluid (CSF) leak conspicuity and image quality as visualized using 3D versus 2D magnetic resonance (MR) myelography in patients with spinal CSF leaks.

Methods: Eighteen patients underwent spinal MR imaging at 3 Tesla. Three board-certified radiologists independently evaluated CSF leak conspicuity and image quality on a 4-point scale; the latter assessed by scoring fat suppression, venous visualization, and severity of CSF flow artifacts.

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  • This study focuses on the incidence and prevalence of stuttering in 3-year-old children in Japan, as few studies have examined this disorder in the country.
  • A questionnaire was used on 2,055 children to screen for stuttering, with positive cases confirmed through interviews and assessments by professionals.
  • The findings showed a prevalence of 6.5% for current stuttering and 8.9% when accounting for past stuttering, with higher risks associated with family history and concerns about the child's development.
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Background: The optimal limb position during stress ultrasound (SUS) evaluation of elbow valgus laxity has not been standardized.

Purpose: To compare 2 elbow positions (at 90° and 30° of flexion) and report which position method better represents the increased valgus laxity characteristics of baseball players.

Study Design: Controlled laboratory study.

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Background: Totally implantable central venous access ports, are required for various purposes, ranging from chemotherapy to nutrition. Port infection is a common complication. In many patients with port infection, the ports are removed because antibiotics are ineffective.

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  • A two-year on-field screening for elbow injuries was conducted on 160 elementary school baseball players in Ibaraki, Japan, focusing on pitcher's and catcher's health in collaboration with the local baseball federation.* -
  • Out of 135 screened players, 10 were diagnosed with osteochondritis dissecans of the humeral capitellum (OCD), with seven being asymptomatic at the time of diagnosis.* -
  • The study identified limited elbow motion and pain during extension as key risk factors for OCD, paving the way for more effective future screenings.*
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This study investigated the use of an upper limb hybrid assistive limb for elbow flexion biofeedback training in recovery from brachial plexus injury in both the postoperative and chronic phases. No adverse events were observed in any patient.: IV.

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  • Developed a 3D CNN method for automatic kidney segmentation in chronic kidney disease patients using MRI images, focusing on different types of Dixon-based MRI.
  • The study involved 100 participants with renal dysfunction and 70 without, with evaluations conducted separately for both groups for accuracy checks.
  • The model achieved high performance on non-RD group data, notably the IP image yielding a Dice score of 0.902, and offers potential for future research in assessing kidney volume and related analyses in CKD patients.
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The eukaryotic nucleus exhibits remarkable plasticity in size, adjusting dynamically to changes in cellular conditions such as during development and differentiation, and across species. Traditionally, the supply of structural constituents to the nuclear envelope has been proposed as the principal determinant of nuclear size. However, recent experimental and theoretical analyses have provided an alternative perspective, which emphasizes the crucial role of physical forces such as osmotic pressure and chromatin repulsion forces in regulating nuclear size.

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We review a nerve suture method for size-mismatched nerve transfers and report a case series involving patients with brachial plexus injury who underwent intercostal-to-musculocutaneous nerve transfer using this method.

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Background: In nerve transfer for peripheral nerve injury, it is sometimes necessary to suture size-mismatched nerves. In 1993, a favorable suture method called the Ochiai suture method for size-mismatched nerve transfer was reported. However, there is currently a lack of substantial evidence beyond the original report.

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