Publications by authors named "Yuke Mao"
Epidermal growth factor receptor (EGFR)-targeted drugs (erlotinib, etc.) are used to treat multiple types of tumours. EGFR is highly expressed in most triple-negative breast cancer (TNBC) patients.
View Article and Find Full Text PDFBackground: Immunotherapy has revolutionized cancer treatment. Recent studies have suggested that the efficacy of immunotherapy can be further enhanced by the influence of gut microbiota. In this study, we aimed to investigate the impact of bacteria on the effectiveness of cancer immunotherapy by combining analysis of clinical samples with validation in animal models.
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- Hyperglycemia negatively impacts stroke recovery, but it's unclear if strict glucose control improves outcomes during acute stroke periods; this study performed a meta-analysis to explore this relationship.
- The analysis included 15 randomized controlled trials with a focus on the effects of tight versus loose glycemic control on stroke patients within 24 hours after onset, measuring outcomes like 90-day mortality and disability scores.
- Results indicated no significant difference in 90-day mortality between those receiving tight glycemic control and those receiving loose control, suggesting that strict management may not confer additional benefits on survival following a stroke.