Publications by authors named "Yukchiu Chung"
Objectives: Remitting seronegative symmetrical synovitis with pitting edema (RSPE) is a rare inflammatory arthritis, with a higher incidence of malignancy. The aim of this study is to identify biomarkers for predicting malignancy in RSPE.
Methods: A total of 51 patients with RSPE from September 2007 to May 2019 were retrospectively reviewed and followed for up to 5 years, with 15 patients with osteoarthritis (OA) and 14 patients with elderly-onset rheumatoid arthritis (EORA) as disease controls.
Article Synopsis
- - Psoriatic arthritis (PsA) is linked to psoriasis and bone damage, with Dkk-1 being a key inhibitor in the Wnt signaling pathway that affects bone health.
- - A study measured serum Dkk-1 levels in 69 PsA patients, 39 rheumatoid arthritis patients, and 21 healthy controls, revealing elevated levels in 68.1% of PsA patients compared to lower levels in healthy individuals.
- - The findings suggest that high serum Dkk-1 correlates with joint swelling and is a significant risk factor for bone erosion in PsA, indicating its potential role in the disease's pathology.