Assessment of ramus, condyle, masseter muscle, and occlusal force before and after sagittal split ramus osteotomy in patients with mandibular prognathism.

Purpose: The purpose of this study was to examine the relationship between the morphologies of the masseter muscle and the ramus and occlusal force before and after sagittal split ramus osteotomy (SSRO) in patients with mandibular prognathism.

Patients And Methods: The study group consisted of 26 patients with mandibular prognathism. All patients underwent bilateral SSRO as well as 3-dimensional computed tomography on which the masseter muscle, ramus, and condyle were measured preoperatively and at 1 year postoperation.

Determining the anatomy of the descending palatine artery and pterygoid plates with computed tomography in Class III patients.

Purpose: Understanding the anatomy of the pterygomaxillary junction region helps prevent blood loss in Le Fort I osteotomy. Here, we determined the location of the descending palatine artery and the structure of the pterygomaxillary region.

Patients And Methods: The study group consisted of 82 Japanese patients with mandibular prognathism and asymmetry, with and without maxillary retrognathism or asymmetry.

Evaluation of bone formation after sagittal split ramus osteotomy with bent plate fixation using computed tomography.

Purpose: To evaluate bone formation between the proximal and distal segments after a sagittal split ramus osteotomy (SSRO) with bent plate fixation.

Patients And Methods: The subjects were 23 patients (46 sides) who underwent bilateral SSRO setback surgery. They were divided into titanium and absorbable plate groups.

Assessment of pterygomaxillary separation in Le Fort I Osteotomy in class III patients.

Purpose: To examine the separation of the pterygomaxillary region at the posterior nasal spine level after Le Fort I osteotomy in Class III patients.

Patients And Methods: The study group consisted of 37 Japanese patients with mandibular prognathism and asymmetry, with maxillary retrognathism or asymmetry. A total of 74 sides were examined.

Changes in the duration of the chewing cycle in patients with skeletal class III with and without asymmetry before and after orthognathic surgery.

Purpose: The purpose of this study was to examine the changes in the chewing rhythm before and after mandibular ramus osteotomy in patients with prognathism with and without asymmetry.

Patients And Methods: We divided 12 men and 22 women with mandibular prognathism into groups on the basis of symmetry and osteotomy procedure. The duration of the chewing cycle was recorded preoperatively and postoperatively.

Statin-induced bone morphogenetic protein (BMP) 2 expression during bone regeneration: an immunohistochemical study.

Objectives: The purpose of this study was to investigate bone morphogenetic protein (BMP) 2 expression after implantation of a statin and recombinant human BMP-2 (rhBMP-2) and to compare the bone regeneration capability of these substances in the rabbit nasal bone using immunohistologic methods.

Study Design: Twelve adult male Japanese white rabbits (n = 12; age 12-16 weeks, weight 2.5-3.

Horizontal changes in the condylar head after sagittal split ramus osteotomy with bent plate fixation.

Objective: The purpose of this study was to evaluate the horizontal changes in the condylar head with bent plate fixation after sagittal split ramus osteotomy (SSRO) with and without a Le Fort I osteotomy.

Study Design: Of 47 Japanese patients with mandibular prognathism, 24 underwent SSRO and 23 underwent SSRO in combination with a Le Fort I osteotomy. A 3-5-mm gap was made between the proximal and distal segments, and a bent plate was fixed with 4 screws in each side of the mandible.

The evaluation of surgical factors related to recovery period of upper lip hypoaesthesia after Le Fort I osteotomy.

Purpose: It is unclear whether surgical factors can affect the upper lip sensitivity. The aim of this study was to assess the factors that can affect the recovery period of hypoaesthesia of the upper lip after Le Fort I osteotomy, using trigeminal somatosensory evoked potential (TSEP) objectively.

Patients And Methods: Twenty-nine patients with mandibular prognathism underwent Le Fort I osteotomy with and without artificial pterygoid plate fracture.

Skeletal stability after mandibular setback surgery: bicortical fixation using a 2.0-mm locking plate system versus monocortical fixation using a nonlocking plate system.

Purpose: This study was conducted to compare the time-course changes in condylar long-axis and skeletal stability after sagittal split ramus osteotomy (SSRO) with bicortical plate fixation versus monocortical plate fixation.

Patients And Methods: Of a group of 40 Japanese patients diagnosed with mandibular prognathism, 20 underwent SSRO with bicortical plate fixation using a locking plate system and the other 20 underwent SSRO with monocortical plate fixation using a conventional plate system. The time-course changes in condylar long-axis and skeletal stability were assessed through axial, frontal, and lateral cephalograms.

A comparative CT evaluation of pharyngeal airway changes in class III patients receiving bimaxillary surgery or mandibular setback surgery.

Objective: The purpose of this study was to compare the morphologic changes of the upper airway space in Class III patients who underwent mandibular setback or bimaxillary surgery (maxillary advancement and mandibular setback) by computed tomography at 2 levels: soft palate and base of tongue.

Methods: The sample consisted of 47 subjects in 2 groups who had been diagnosed as having Class III skeletal deformities and had been treated by mandibular setback or bimaxillary surgery (maxillary advancement and mandibular setback). Anteroposterior, lateral, and cross-sectional area dimensions of the airway at the level of soft palate and base of tongue were measured pre- and postoperatively on computed tomography images.

Assessment of the relationship between the recovery of maximum mandibular opening and the maxillomandibular fixation period after orthognathic surgery.

Purpose: The purpose of this study was to evaluate the differences in the recovery of maximum mandibular opening (MMO), and the relationship between MMO and the maxillomandibular fixation (MMF) period after sagittal split ramus osteotomy (SSRO) and intraoral vertical ramus osteotomy (IVRO), with and without Le Fort I osteotomy.

Patients And Methods: Sixty-eight patients with diagnosed mandibular prognathism with or without asymmetry were divided into 4 groups (SSRO, IVRO, SSRO with Le Fort I osteotomy, and IVRO with Le Fort I osteotomy). MMO and the MMF period were measured preoperatively and at 1, 3, 6, 12, and 18 months after surgery.

Relationship between recovery period of lower lip hypoesthesia and sagittal split area or plate screw position after sagittal split ramus osteotomy.

Objective: The purpose of this study was to objectively evaluate the relationship between recovery of hypoesthesia of the lower lip after sagittal split ramus osteotomy (SSRO) with trigeminal somatosensory evoked potential (TSEP) and sagittal split area or plate screw position, using postoperative computerized tomography (CT).

Study Design: The subjects consisted of 58 patients (116 sides) with mandibular prognathism who underwent SSRO. The patients were divided into 2 groups.

A comparison of lower lip hypoesthesia measured by trigeminal somatosensory-evoked potential between different types of mandibular osteotomies and fixation.

Purpose: The purpose of this study was to compare objectively, the recovery of hypoestheia of the lower lip following orthognathic surgery using different procedures (sagittal split ramus osteotomy [SSRO]) and intra-oral vertical ramus osteotomy (IVRO)) and fixation methods (monocortical plate fixation and bi-cortical plate fixation). Hypoesthesia was evaluated using the trigeminal somatosensory-evoked potential (TSEP).

Patients And Methods: The subjects consisted of 174 patients (348 sides) with mandibular prognathism with or without asymmetry, who underwent mandibular ramus osteotomies using different fixation types.

Comparison of maxillary stability after Le Fort I osteotomy for occlusal cant correction surgery and maxillary advanced surgery.

Objective: To compare postoperative maxillary stability following Le Fort I osteotomy for the correction of occlusal cant as compared with conventional Le Fort I osteotomy for maxillary advancement.

Study Design: The subjects were 40 Japanese adults with jaw deformities. Of these, 20 underwent a Le Fort I osteotomy and intraoral vertical ramus osteotomy (IVRO) to correct asymmetric skeletal morphology and inclined occlusal cant.

Condylar and disc positions after sagittal split ramus osteotomy with and without Le Fort I osteotomy.

Purpose: The purpose of this study is to examine the changes in temporomandibular joint (TMJ) morphology and clinical symptoms after sagittal split ramus osteotomy (SSRO) with and without a Le Fort I osteotomy.

Subjects And Methods: Of 45 Japanese patients with mandibular prognathism, 23 underwent SSRO and 22 underwent SSRO in combination with a Le Fort I osteotomy. The TMJ symptoms and joint morphology, including disc tissue, were assessed preoperatively and postoperatively by magnetic resonance imaging (MRI) and axial cephalography.

Evaluation of upper lip hypoesthesia with a trigeminal somatosensory-evoked potential following Le Fort I osteotomy in combination with mandibular osteotomy.

Purpose: The purpose of this study was to objectively evaluate hypoesthesia of the upper lip following Le Fort I osteotomy in combination with mandibular osteotomy with trigeminal somatosensory evoked potential (TSEP).

Subjects And Methods: The subjects consisted of 25 patients with mandibular prognathism with maxillary retrognathism mandibular prognathism with or without asymmetry, who underwent Le Fort I osteotomy in combination with sagittal split ramus osteotomy (SSRO) or intraoral vertical ramus osteotomy (IVRO). Trigeminal nerve hypoesthesia at the region of the upper lip was assessed bilaterally by the TSEP method.

Inhibition of invasion and metastasis in oral cancer by targeting urokinase-type plasminogen activator receptor.

There have been reports of strong correlations between poor prognosis in various cancers and concomitant expression of urokinase-type plasminogen activator (uPA) and its surface receptor (uPAR). We and others have previously shown that the uPA system plays a significant role in a subset of head and neck squamous cell carcinoma. In the present study, we found that uPAR is required for invasion and metastasis of highly malignant oral cancer cells (OSC-19).