Publications by authors named "Yukai Chen"

Rationale: Gastric antral vascular ectasia (GAVE) is a rare acquired lesion characterized by vascular dilation in the gastric antrum, frequently results in occult or overt gastrointestinal bleeding. Endoscopic intervention remains the cornerstone of therapy. Argon plasma coagulation was previously considered a first treatment option.

View Article and Find Full Text PDF

Background: Capecitabine, a prodrug of 5-fluorouracil, is extensively utilized for the treatment of metastatic breast cancer, colorectal cancer, and gastric cancer. Nevertheless, there exist limitations in comprehending adverse reactions (AEs) in clinical practice. In this study, we investigated the distribution of AEs associated with capecitabine and explored potential rare adverse reactions by mining the Food and Drug Administration Adverse Event Reporting System (FAERS).

View Article and Find Full Text PDF

The recombination of photoinduced carriers hampers the photocatalysis process. Construction of the heterojunction and built-in piezoelectric field boosts the separation of electrons and holes. Herein, a novel magnetic recyclable SnFeO(SFO)/ZnO composite with enhanced photocatalytic performance based on the dual electric field synergism was proposed for the first time.

View Article and Find Full Text PDF

IGFALS forms stable ternary complexes with insulin-like growth factors (IGF1 and IGF2) and IGF-binding proteins (IGFBP3 and IGFBP5), which prolong the half-lives of IGFs. Through immunohistochemical analysis of 90 pairs of clinical samples and bioinformatics analysis, we observed downregulation of IGFALS in hepatocellular carcinoma tissues, which was associated with poor patient prognosis. This prompted us to explore the specific molecular mechanism of action of IGFALS in the inhibition of hepatocellular carcinoma (HCC), which could be a potential new target for the treatment of HCC.

View Article and Find Full Text PDF
Article Synopsis
  • Adult intussusception is rare in adults and is not often linked to cancer, but a case was reported involving a 31-year-old male with ileocecal intussusception caused by metastatic melanoma.
  • The patient had a history of scalp melanoma and presented with chronic lower abdominal pain; diagnostic tests like CT and colonoscopy confirmed the condition.
  • Laparoscopic surgery was performed to remove the affected bowel segment, and the patient made a smooth recovery, highlighting the need to consider cancer in adult intussusception cases and the importance of timely surgical treatment.
View Article and Find Full Text PDF

CO-selective photoreduction to value-added products is ideal, but its practical application suffers from weak photogenerated carrier separation and insufficient multielectron transport. Herein, we constructed the tricomponent AuNPs@SnO-AuNCs hybrid by decorating Au nanoclusters (AuNCs) on the Au nanoparticle (AuNPs)@SnO core-shell structure. AuNC-NP dual coupling endowed AuNPs@SnO-AuNCs with an excellent CO yield of 64.

View Article and Find Full Text PDF

Near-infrared (NIR) light, accounting for approximately 50 % of solar light, cannot directly excite photocatalytic reactions due to its lower energy, which severely restricts the photocatalytic solar energy conversion efficiency and hinders the application of photocatalysis. To overcome this dilemma, some viable strategies have been proposed to harness NIR light for enhancing photocatalytic performance based on material structure, composition, and function designs, and obvious progresses have been witnessed. In this review, the basic principles and representative advances in photocatalyst heterojunction designs (including p-n junctions, S-scheme, Z-scheme, and type-ІІ heterojunctions), photocatalyst composition and function designs (such as preparing rare earth element doped upconversion photocatalysts, rare earth upconversion photocatalytic hybrids and triplet-triplet annihilation upconversion photocatalytic composites), and photothermal-photocatalytic bifunction designs for NIR light utilization are exclusively scrutinized.

View Article and Find Full Text PDF
Article Synopsis
  • Mephedrone, a synthetic drug popular in the late 2000s for recreational use, has been linked to both intoxication and fatalities, prompting this study to analyze blood concentration levels in such cases.
  • The review included 77 cases, revealing that 34 resulted in death and 43 were non-fatal, with a median age of 24 years and a significant majority being male; higher blood concentrations were observed in fatal cases.
  • Findings indicate that blood mephedrone levels in deceased individuals are about 11 times greater than in non-fatal cases, suggesting a need for further research to standardize diagnostic methods and evaluate the implications for treatment and prognosis.
View Article and Find Full Text PDF
Article Synopsis
  • Seipin is a key protein that helps in the assembly of lipid droplets (LDs) by organizing lipid packaging at the interface of the endoplasmic reticulum and LDs.
  • Researchers identified four proteins (Ldo45, Ldo16, Tgl4, and Pln1) that are only recruited to seipin when its function is intact, indicating they are important for LD formation.
  • Disruption of seipin function leads to uneven distribution of these proteins and abnormal LDs, while overexpressing any of the accessory factors causes LD aggregation, underscoring their importance and the need for proper balance in their amounts.
View Article and Find Full Text PDF

The microreactor could break the limitation of mass transfer and photon transmission in photocatalysis. Through a facile assembly method, a planar photocatalytic microreactor was constructed to fit most of the photocatalysts regardless of their strict preparation method. This microreactor exhibits a 2.

View Article and Find Full Text PDF
Article Synopsis
  • Habitat fragmentation has reduced species distribution and increased extinction risk, particularly for small populations like Chieniodendron hainanense, a wild plant in need of urgent conservation.
  • Understanding the genetic diversity of C. hainanense is crucial for addressing its vulnerability and creating effective conservation strategies.
  • Our study examined 35 specimens from six populations using genotyping techniques, revealing limited genetic diversity and weak differentiation among populations, which may be influenced by natural selection.
View Article and Find Full Text PDF

By constructing a AgO/BiOI p-n heterojunction and applying a heat-localization microreactor, efficient photocatalysis enhanced by both photoinduced carrier separation and the photothermal effect was realized. This work focuses on the utilization of near-infrared light to broaden the absorption spectrum and accelerate the transportation of carriers. Through the production and localization of heat, it provides a novel thought for full-spectrum photocatalysis.

View Article and Find Full Text PDF

Owing to its unique layered structure, BiOCl demonstrates high photocatalytic activity. However, its wide bandgap hinders the absorption of visible light. Doping modification is an effective method to expand the light absorption edge of photocatalysts by creating a doping energy level within the bandgap.

View Article and Find Full Text PDF

Purpose: Although customized three-dimensional (3D) templates have shown advantages in brachytherapy, widespread application is still full of challenges. The present work proposed the use of a commercial 3D standardized template-guided intracavitary/interstitial brachytherapy (IC/ISBT) that could provide simple and reproducible needles' insertion.

Material And Methods: 43 patients received external beam radiotherapy (EBRT) with 45-50.

View Article and Find Full Text PDF

This study explored the influence of climatic oscillations on the striped, blue, and silver marlin catch rates in the Indian Ocean by using logbook data from Taiwanese large-scale fishing vessels and climate records from 1994 to 2016. Only the Madden-Julian oscillation (MJO) and the subtropical Indian Ocean dipole (SIOD) had immediate effects on the striped and silver marlin catch rates. The positive and negative phases of the IOD at the lags of 7 and 3 years corresponded to increased and decreased catch rates, respectively, for both the striped and blue marlin, contrasting to the reverse pattern for the silver marlin.

View Article and Find Full Text PDF

The stimulator of interferon genes (STING) is a crucial signaling hub in the immune system's antiviral and antimicrobial defense by detecting exogenous and endogenous DNA. The multifaceted functions of STING have been uncovered gradually during past decades, including homeostasis maintenance and overfull immunity or inflammation induction. However, the subcellular regulation of STING and mitochondria is poorly understood.

View Article and Find Full Text PDF

Hindering the recombination of photoinduced electron-hole pairs is of significance for enhancing photocatalytic performance. Applying a voltage to separate carriers offers an option to realize it. Thermoelectric materials own the ability to continuously sustain a voltage when a temperature difference exists between its two sides.

View Article and Find Full Text PDF

Purpose: The purpose of this study was to investigate the precision of deep learning (DL)-based auto-reconstruction in localizing interstitial needles in post-operative cervical cancer brachytherapy (BT) using three-dimensional (3D) computed tomography (CT) images.

Material And Methods: A convolutional neural network (CNN) was developed and presented for automatic reconstruction of interstitial needles. Data of 70 post-operative cervical cancer patients who received CT-based BT were used to train and test this DL model.

View Article and Find Full Text PDF

. Accurate image registration is an important step in online image-guided adaptive radiotherapy. The aim of this study was to investigate the effects of different factors on registration accuracy in a magnetic resonance (MR)-guided adaptive radiotherapy workflow.

View Article and Find Full Text PDF

The location, effort, number of captures, and time of fishing were all used in this study to assess the geographic distribution of in the Taiwan Strait. Other species distribution models performed worse than generalized linear models (GLMs) based on six oceanographic parameters. The sea surface temperature (SST) was between 26.

View Article and Find Full Text PDF

. The purpose of this study was to evaluate the accuracy of brachytherapy (BT) planning structures derived from Deep learning (DL) based auto-segmentation compared with standard manual delineation for postoperative cervical cancer..

View Article and Find Full Text PDF

Utilization of low-energy photons for efficient photocatalysis remains a challenging pursuit. Herein, a strategy is reported to boost the photocatalytic performance, by promoting low-energy photons dual harvest through bimodal surface plasmon resonance (SPR)-enhanced synergistically upconversion and pyroelectricity. It is achieved by introducing triplet-triplet annihilation upconversion (TTA-UC) materials and plasmonic material (Au nanorods, AuNRs) into composite fibers composed of pyroelectric substrate (poly(vinylidene fluoride)) and photocatalyst Cd Zn S.

View Article and Find Full Text PDF

(Dipterocarpaceae) is an endangered tree species restricted to Hainan Island, China, and a small part of Northern Vietnam. On Hainan Island, it is an important indicator species for tropical forests. The wood of has a very high utilization value in nature since it is compact in structure, hard in texture, not easily deformed after drying, durable, and resistant to sunlight and water.

View Article and Find Full Text PDF

To demonstrate the trends and variety of research on palliative care during the COVID-19 pandemic. A systematic search of the Web of Science database. Since the outbroke of the COVID-19 pandemic, the adjustment of palliative care systems is warranted to maintain a high quality of care.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_session7hj3n7jo5pdvbsb3h3fhnfv78aeufifq): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once