Hybrid approach in sacral sore management with maggot debridement therapy and flap reconstruction.

Sacral sore is a common problem in patients with spinal cord injury. It leads to prolonged hospitalization and recurrent infections which might require repeated surgery to treat. Flap reconstruction allows soft tissue coverage of sacral sore under the premise of infection-free wound base.

Chicken proximal interphalangeal joint as an animal model for human finger joint prosthesis evaluation.

A group of chickens was employed as animal model for evaluation of osteointegration, stability and to a lesser extent, functional recovery potential of a newly designed human finger joint prosthesis under long term implantation. Mechanical and Histological test was conducted. Results in our study suggest that while chicken interphalangeal joint could be a potential model for evaluating surgical operation and osteointegration of human finger joint prosthesis, the effectiveness of evaluation in certain areas are far from ideal especially in functional and mechanical evaluation of the prosthesis.

The measured mechanical properties of osteoporotic trabecular bone decline with the increment of deformation volume during micro-indentation.

Purpose: Osteoporosis is a critical global health issue. However, the biomechanical properties of osteoporotic trabecular bone have not been well understood due to its hierarchically complex structure mingled with accumulated microcracks. Previous studies indicated the mechanical behaviors of trabecular bone may differ with varying amounts of deformation.

Biological Evaluation of Flexible Polyurethane/Poly l-Lactic Acid Composite Scaffold as a Potential Filler for Bone Regeneration.

Degradable bone graft substitute for large-volume bone defects is a continuously developing field in orthopedics. With the advance in biomaterial in past decades, a wide range of new materials has been investigated for their potential in this application. When compared to common biopolymers within the field such as PLA or PCL, elastomers such as polyurethane offer some unique advantages in terms of flexibility.