Histological reassessment of the role of bridging fibrosis in the angioarchitectural features associated with lobular distortion of the liver in chronic viral hepatitis.

Aim: To reassess the role of bridging fibrosis in the lobular distortion of the liver from an angioarchitectural aspect.

Methods: Two tissue samples obtained from surgically resected livers with chronic hepatitis and one obtained from an autopsy case with chronic hepatitis were used for the three-dimensional observation of angioarchitecture by histological reconstruction.

Results: Samples showed bridging fibrosis with various degrees of severity, without cirrhotic changes.