Publications by authors named "Yujie Chai"
In this study, we successfully integrated the full-length genome of the cyanophage PP into the non-host cyanobacterium Synechococcus elongatus PCC 7942, facilitated by conjugation via Escherichia coli. To address the challenge posed by the toxic open reading frames (ORFs) of PP in E. coli, we first identified and characterized three toxic ORFs.
View Article and Find Full Text PDFArticle Synopsis
- This study investigates the potential of three biomarkers (REG3α, sST2, and TNFR1) in blood as predictors for the severity and outcome of acute graft-versus-host disease (aGVHD) in children post-transplant.
- Data from 70 aGVHD patients and 30 healthy children were analyzed, revealing higher levels of these biomarkers in more severe cases of aGVHD and in those with poor treatment outcomes.
- The combined analysis of all three markers showed enhanced predictive accuracy for aGVHD prognosis, outperforming the use of each marker individually or in pairs.
Background: Previous studies have indicated a potential link between the gut microbiota and lymphoma. However, the exact causal interplay between the two remains an area of ambiguity.
Methods: We performed a two-sample Mendelian randomization (MR) analysis to elucidate the causal relationship between gut microbiota and five types of lymphoma.